OR7E85BP: A GPCR Involved in Brain Function and Regulation (G650293)

OR7E85BP: A GPCR Involved in Brain Function and Regulation

OR7E85BP (LOC650293) is a protein that is expressed in various tissues of the body, including the brain, heart, kidneys, and liver. Its full name is ornitin-conjugated 7-transmembrane receptor subfamily 8 member 5, and it is a member of the G protein-coupled receptor (GPCR) family.

GPCR is a large family of transmembrane proteins that play a crucial role in cellular signaling. They are involved in a wide range of physiological processes, including sensory perception, neurotransmitter signaling, and hormone signaling. GPCRs are also known as G protein-coupled receptors, because they are involved in the interaction with G proteins, which are responsible for transmitting signals from the cell surface to the inside of the cell.

OR7E85BP is a GPCR that is expressed in the brain and is involved in the regulation of various physiological processes that are critical for brain function. One of its functions is to regulate the release of neurotransmitters, such as dopamine and serotonin, which are involved in mood, emotion, and other cognitive processes.

In addition to its role in neurotransmission, OR7E85BP is also involved in the regulation of ion channels in the brain. Specifically, it is known to be involved in the regulation of the K+ channel, which is involved in the flow of electrical signals in the brain. This is important for the proper functioning of the brain, as changes in the levels of K+ in the brain can have a significant impact on cognitive processes.

OR7E85BP is also involved in the regulation of cell survival and proliferation. It is known to be involved in the formation of blood-brain barrier (BBB), which is a barrier that separates the brain from the blood and helps to protect it from harmful substances. The BBB is made up of tight junctions, which are specialized Gap junction proteins (GJP) that help to maintain the integrity of the blood-brain barrier. OR7E85BP is thought to be involved in the regulation of tight junction formation and may play a role in the development of certain neurological disorders.

OR7E85BP is also involved in the regulation of inflammation. It is known to be involved in the regulation of the production of pro-inflammatory cytokines, which are important for the immune response. This is important for maintaining the integrity of the immune system and for protecting the body against infection.

In conclusion, OR7E85BP is a GPCR that is involved in the regulation of various physiological processes that are critical for brain function. Its functions include the regulation of neurotransmission, ion channels, cell survival and proliferation, and inflammation. As a potential drug target, OR7E85BP is a promising target for the development of new treatments for a wide range of neurological disorders. Further research is needed to fully understand the role of OR7E85BP in the regulation of brain function and to develop effective treatments.

Protein Name: Olfactory Receptor Family 7 Subfamily E Member 85B Pseudogene

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•   general information;
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•   the target screening and validation;
•   expression level;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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