Potential Drug Target and Biomarker for Neurological Disorders: Olfactory Receptor OR8B12
Potential Drug Target and Biomarker for Neurological Disorders: Olfactory Receptor OR8B12
Olfactory receptor OR8B12 is a protein that is expressed in the olfactory system of the human body, which is responsible for the sense of smell. OR8B12 has been identified as a potential drug target and a biomarker for various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression.
The olfactory system is a complex system of specialized neurons that is responsible for detecting and recognizing scents. The sense of smell is a critical aspect of human life, as it allows us to identify and enjoy a variety of smells, such as those of our food, the environment, and other people. Olfactory receptors are a key component of the olfactory system, and they are responsible for transmitting the sense of smell to the brain.
OR8B12 is a olfactory receptor that is expressed in the olfactory system of the human body. It is a 190-kDa protein that is composed of a single transmembrane domain and an intracellular tail. OR8B12 is expressed in the olfactory system of the brain and is involved in the sense of smell.
In recent years, OR8B12 has been identified as a potential drug target and a biomarker for a variety of neurological and psychiatric disorders. Studies have shown that altered levels of OR8B12 have been detected in the brains of individuals with Alzheimer's disease, Parkinson's disease, and depression. Additionally, OR8B12 has been shown to be involved in the development and progression of these disorders.
One of the potential benefits of targeting OR8B12 as a drug target is its potential to treat neurodegenerative disorders. Alzheimer's disease, in particular, is a progressive neurodegenerative disorder that is characterized by the progressive loss of brain cells. The sense of smell is thought to be an important factor in the development and progression of Alzheimer's disease, and targeting OR8B12 as a drug target may be a promising approach to treating this disorder.
Another potential benefit of targeting OR8B12 as a drug target is its potential to treat psychiatric disorders. Studies have shown that altered levels of OR8B12 have been detected in the brains of individuals with depression and that OR8B12 may be involved in the development and progression of this disorder. Targeting OR8B12 as a drug target may be a promising approach to treating depression and other psychiatric disorders.
In addition to its potential as a drug target and biomarker, OR8B12 has also been shown to be involved in the regulation of the olfactory system. Studies have shown that OR8B12 is involved in the regulation of the outflow of olfactory neurons, which is important for the sense of smell. Additionally, OR8B12 has been shown to be involved in the regulation of the expression of genes involved in olfactory development and function.
Overall, OR8B12 is a protein that is involved in the olfactory system of the human body. Its potential as a drug target and biomarker for a variety of neurological and psychiatric disorders makes it an attractive target for research and development of new treatments. Further studies are needed to fully understand the role of OR8B12 in the sense of smell and its potential as a drug target and biomarker.
Protein Name: Olfactory Receptor Family 8 Subfamily B Member 12
Functions: Odorant receptor
The "OR8B12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OR8B12 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
OR8B2 | OR8B3 | OR8B4 | OR8B6P | OR8B7P | OR8B8 | OR8D1 | OR8D2 | OR8D4 | OR8F1P | OR8G1 | OR8G2P | OR8G3P | OR8G5 | OR8G7P | OR8H1 | OR8H2 | OR8H3 | OR8I2 | OR8J1 | OR8J3 | OR8K1 | OR8K3 | OR8K5 | OR8S1 | OR8U1 | OR8U3 | OR8U8 | OR9A1P | OR9A2 | OR9A4 | OR9G1 | OR9G4 | OR9G9 | OR9H1P | OR9I1 | OR9K2 | OR9Q1 | OR9Q2 | ORAI1 | ORAI2 | ORAI3 | ORC1 | ORC2 | ORC3 | ORC4 | ORC5 | ORC6 | Orexin receptor | Organic anion transporters (OATs) | Organic cation transporter | Origin recognition complex | ORM1 | ORM2 | ORMDL1 | ORMDL2 | ORMDL3 | OS9 | OSBP | OSBP2 | OSBPL10 | OSBPL11 | OSBPL1A | OSBPL2 | OSBPL3 | OSBPL5 | OSBPL6 | OSBPL7 | OSBPL8 | OSBPL9 | OSCAR | OSCP1 | OSER1 | OSER1-DT | OSGEP | OSGEPL1 | OSGEPL1-AS1 | OSGIN1 | OSGIN2 | OSM | OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1
