GJB3: A Potential Drug Target and Biomarker for Cancer (G2707)

Target Name: GJB3

NCBI ID: G2707

GJB3

GJB3: A Potential Drug Target and Biomarker for Cancer

GJB3 (Gene JU504987) is a gene that has been identified as a potential drug target and biomarker for various diseases, including cancer. The gene is located on chromosome 6p21.3 and encodes for a protein known as GJB3. GJB3 is a transmembrane protein that is expressed in various tissues and cells throughout the body, including the brain, heart, and liver. Its function is not well understood, but it is known to be involved in several cellular processes, including cell adhesion, migration, and invasion.

One of the most promising aspects of GJB3 is its potential as a drug target. GJB3 has been shown to be involved in several signaling pathways that are involved in the development and progression of cancer. For example, GJB3 has been shown to be involved in the regulation of theNotch signaling pathway, which is a well-established pathway that is involved in the development of many types of cancer. In addition, GJB3 has also been shown to be involved in the regulation of the TGF-β signaling pathway, which is also involved in the development of cancer.

Another promising aspect of GJB3 is its potential as a biomarker. GJB3 has been shown to be expressed in a variety of cancer types, including breast, ovarian, and prostate cancer. Additionally, GJB3 has been shown to be involved in the regulation of cell cycle progression, which is a key aspect of cancer development. This suggests that GJB3 may be a useful biomarker for the diagnosis and treatment of cancer.

In addition to its potential as a drug target and biomarker, GJB3 is also of interest because of its location on chromosome 6p21.3. This suggests that it may be located in a region of the genome that is commonly deleted in cancer, which could make it an attractive target for drugs that are able to restore gene function in cancer cells.

Overall, GJB3 is a gene that has a lot of potential as a drug target and biomarker for cancer. Further research is needed to fully understand its function and to determine its utility as a therapeutic target.

Protein Name: Gap Junction Protein Beta 3

Functions: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell

The "GJB3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about GJB3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets