Target Name: RCOR2
NCBI ID: G283248
Review Report on RCOR2 Target / Biomarker Content of Review Report on RCOR2 Target / Biomarker
RCOR2
Other Name(s): REST corepressor 2 (isoform 1) | RCOR2 variant 1 | REST corepressor 2, transcript variant 1 | RCOR2_HUMAN | REST corepressor 2

RCOR2: Potential Drug Targets and Biomarkers

REST corepressor 2 (RCOR2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the superfamily of corepressors, which are a group of non-coding RNAs that play a critical role in regulating gene expression. RCOR2 is one of the corepressors that is known to function as a negative regulator of gene expression. This means that when RCOR2 is active, it can repress the activity of other genes, preventing them from being expressed.

The Importance ofRCOR2

RCOR2 has been shown to play a critical role in many physiological processes in the body. One of its most important functions is its role in maintaining homeostasis. RCOR2 is highly expressed in the brain, where it is involved in the regulation of ion channels and neurotransmitter release. It is also expressed in the heart, where it is involved in the regulation of contractility and heart rate. Additionally, RCOR2 is expressed in the kidneys, where it is involved in the regulation of water and electrolyte balance.

In addition to its role in maintaining homeostasis, RCOR2 is also involved in many other important processes in the body. For example, it is involved in the regulation of cell proliferation and differentiation, and it is a negative regulator of the production of pro-inflammatory cytokines. Additionally, RCOR2 is involved in the regulation of protein synthesis and it can also act as a negative regulator of gene expression.

Drug Targeting and Biomarker

The potential drug targets for RCOR2 are vast and varied. One of the main targets is the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These conditions are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles, which are thought to be caused by the build-up of toxic protein aggregates. RCOR2 has been shown to play a critical role in the regulation of the production of these toxic protein aggregates, and therefore it may be a potential drug target.

Another potential drug target for RCOR2 is the regulation of inflammation. Chronic inflammation is associated with many diseases, including heart disease, diabetes, and cancer. RCOR2 has been shown to play a critical role in the regulation of inflammation, and therefore it may be a potential biomarker for the assessment of inflammation in diseases.

Finally, RCOR2 may also be a potential drug target for the treatment of depression and anxiety disorders. These conditions are characterized by the persistent feelings of sadness and hopelessness that can interfere with daily life. RCOR2 has been shown to play a critical role in the regulation of mood and anxiety, and therefore it may be a potential drug target.

Conclusion

RCOR2 is a protein that is expressed in various tissues of the body and is involved in the regulation of many important physiological processes. It has been shown to play a critical role in the regulation of homeostasis, cell proliferation and differentiation, protein synthesis, and inflammation. As a result, RCOR2 is a potential drug target for the treatment of many neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, heart disease, diabetes, and cancer. Additionally, RCOR2 may also be a potential biomarker for the assessment of inflammation in diseases and it may be a potential drug target for the treatment of depression and anxiety disorders. Further research is needed to fully understand the role of RCOR2 in the regulation of physiological processes and to develop safe and effective drugs that target RCOR2.

Protein Name: REST Corepressor 2

Functions: May act as a component of a corepressor complex that represses transcription

The "RCOR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RCOR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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RCOR3 | RCSD1 | RCVRN | RD3 | RD3L | RDH10 | RDH11 | RDH12 | RDH13 | RDH14 | RDH16 | RDH5 | RDH8 | RDM1 | RDUR | RDX | RDXP2 | Reactive oxygen species (ROS) | REC114 | REC8 | RECK | RECQL | RECQL4 | RECQL5 | REELD1 | REEP1 | REEP2 | REEP3 | REEP4 | REEP5 | REEP6 | REG1A | REG1B | REG1CP | REG3A | REG3G | REG4 | REL | REL-DT | RELA | Relaxin | Relaxin receptor | RELB | RELCH | RELL1 | RELL2 | RELN | RELT | REM1 | REM2 | REN | RENBP | REP15 | Repeat-binding factor | REPIN1 | Replication factor C | Replication Protein A Complex (RPA) | REPS1 | REPS2 | RER1 | RERE | REREP3 | RERG | RERGL | RESF1 | RESP18 | REST | RET | Retinoid acid receptor | Retinoid RXR receptor | Retinol dehydrogenase | RETN | RETNLB | RETREG1 | RETREG2 | RETREG3 | RETSAT | REV1 | REV3L | Reverse transcriptase (Telomerase) | REX1BD | REXO1 | REXO1L1P | REXO1L2P | REXO1L6P | REXO1L8P | REXO2 | REXO4 | REXO5 | RFC1 | RFC2 | RFC3 | RFC4 | RFC5 | RFESD | RFESDP1 | RFFL | RFK | RFLNA | RFLNB