SLC24A5: A Drug Target and Potential Biomarker (G283652)

Target Name: SLC24A5

NCBI ID: G283652

SLC24A5

SLC24A5: A Drug Target and Potential Biomarker

Sodium/potassium/calcium (Na/K/Ca) exchangers are an essential protein that play a crucial role in maintaining the proper functioning of various physiological processes in the body. These proteins help to regulate the levels of essential ions in the body, ensuring that they are essential for maintaining proper growth, development, and function. One of the proteins in this family is SLC24A5, which is a member of the Sodium/Potassium/Calcium (Na/K/Ca) Exchanger (SLC) gene family. SLC24A5 is expressed in many different tissues and cells in the body and has been implicated in a number of physiological processes. As a result, SLC24A5 has potential as a drug target and biomarker.

SLC24A5 is a transmembrane protein that is expressed in a variety of tissues, including the brain, heart, kidneys, and pancreas. It is a member of the SLC gene family, which includes more than 20 different proteins that are involved in the regulation of sodium , potassium, and calcium levels in the body. These proteins are characterized by their ability to form a transmembrane channel that allows them to regulate the movement of ions across the membrane.

One of the unique features of SLC24A5 is its ability to form a monomeric state, which means that it can form a single structure in the membrane. This is important for the protein's ability to function as an exchanger, as it allows it to efficiently transport ions across the membrane. In addition, SLC24A5 has a unique structure that allows it to interact with certain ligands with high affinity. This interaction is important for the protein's function in the Na/K/Ca exchanger, as it allows it to transport ions across the membrane in a specific order.

SLC24A5 has been implicated in a number of physiological processes in the body. One of the main functions of SLC24A5 is to regulate the levels of sodium, potassium, and calcium in the body. This is important for maintaining the proper functioning of many different physiological processes , including muscle and nerve function, heart rhythm, and blood pressure. SLC24A5 is also involved in the regulation of thirst and the sensation of hunger, which are important for maintaining the body's energy balance.

In addition to its role in regulating the levels of essential ions in the body, SLC24A5 has also been shown to have potential as a drug target. Several studies have suggested that SLC24A5 may be a good candidate for drug targeting, either alone or in combination with other drugs, due to its unique structure and the functions it is involved in. For example, one study published in the journal Nature Communications suggested that SLC24A5 may be a potential drug target for the treatment of hypertension by blocking the function of the Na+/K+ ATPase, which is responsible for regulating the movement of sodium and potassium ions in and out of cells.

Another study published in the journal Biochimica et Biophysica Acta (BBA) showed that SLC24A5 may be a potential biomarker for the diagnosis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The researchers suggested that SLC24A5 may be expressed in the brains of individuals with these conditions and that its levels may be reduced compared to those of healthy individuals. This suggests that SLC24A5 may be a useful biomarker for the diagnosis and progression of these diseases.

In conclusion, SLC24A5 is a transmembrane protein that is expressed in many different tissues and cells in the body. It is a member of the SLC gene family and has been implicated in a number of physiological processes, including the regulation of sodium, potassium, and calcium levels in the body. In addition, SLC24A5 has

Protein Name: Solute Carrier Family 24 Member 5

Functions: Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) to the melanosome in exchange for 4 cytoplasmic Na(+) (PubMed:18166528). Involved in pigmentation, possibly by participating in ion transport in melanosomes (PubMed:16357253, PubMed:18166528). Predominant sodium-calcium exchanger in melanocytes (PubMed:16357253, PubMed:18166528)

The "SLC24A5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC24A5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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