GLUT1DS: A GLucose Transport Protein Implicated in Cancer and Neurodegenerative Diseases

Target Name: SLC2A1

NCBI ID: G6513

SLC2A1

GLUT1DS: A GLucose Transport Protein Implicated in Cancer and Neurodegenerative Diseases

GLUT1DS, also known as SLC2A1, is a gene that encodes a protein known as GLUT1-associated protein 1. This protein is expressed in many different tissues throughout the body and is involved in a variety of cellular processes.

One of the key functions of GLUT1DS is its role in the transport of glucose into the brain. The brain is one of the body's most important organs and relies heavily on the delivery of oxygen and nutrients to maintain its health. In order to do this, the brain needs to be able to efficiently import glucose, which is a critical energy source.

GLUT1DS helps to regulate the movement of glucose into the brain by allowing it to interact with a protein called GLUT1. GLUT1 is a transmembrane protein that is expressed in many different tissues, including the brain. It plays a key role in the regulation of glucose uptake and release, as well as the transport of other molecules into the cell.

In addition to its role in glucose transport, GLUT1DS is also involved in the regulation of a variety of other cellular processes. For example, it has been shown to be involved in the regulation of cell division, and has been shown to play a role in the development of cancer.

As a drug target, GLUT1DS is an attractive target for researchers because of its involvement in a variety of cellular processes that are important for human health. It is also a good candidate for a biomarker, as its expression has been shown to be associated with a number of diseases, including cancer, diabetes, and neurodegenerative diseases.

In conclusion, GLUT1DS is a gene that encodes a protein that is involved in a variety of cellular processes, including the regulation of glucose transport and the development of cancer. As a drug target, it is an attractive target for researchers because of its involvement in these processes, as well as its potential as a biomarker. Further research is needed to fully understand the role of GLUT1DS in human health and disease.

Protein Name: Solute Carrier Family 2 Member 1

Functions: Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake (PubMed:18245775, PubMed:19449892, PubMed:25982116, PubMed:27078104, PubMed:10227690). Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses (PubMed:18245775, PubMed:19449892). Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain (PubMed:10227690). In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity)

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