SLC26A3: A Potential Drug Target and Biomarker (G1811)

Target Name: SLC26A3

NCBI ID: G1811

SLC26A3

SLC26A3: A Potential Drug Target and Biomarker

Sodium-glucose cotransporter 2 (SLC26A3) is a gene that encodes a protein known as GLUT2, which is a transmembrane protein that plays a critical role in the regulation of glucose transport and metabolism in various tissues and cells. The GLUT2 gene has been identified as a potential drug target in the field of diabetes due to its involvement in the glucose uptake and storage. GLUT2 has also been shown to be overexpressed in various diseases, including cancer, which suggests that it may have potential as a biomarker for disease diagnosis and monitoring.

SLC26A3 is a single exon gene that encodes the GLUT2 protein. The gene has a length of 26 amino acid residues and is located on chromosome 12q34. SLC26A3 is a member of the SLC gene family, which includes several related genes that encode for proteins involved in the transport and regulation of various types of solutes, including glucose. The SLC gene family is one of the most widely studied gene families in the field of gene expression and has been implicated in many cellular processes, including glucose metabolism, insulin signaling, and neural function.

GLUT2 is a transmembrane protein that is expressed in various tissues and cells throughout the body. It is involved in the regulation of glucose transport and metabolism by participating in several different signaling pathways. GLUT2 has been shown to play a critical role in the uptake and storage of glucose in the liver, muscle, and fat tissues. It is also involved in the regulation of insulin sensitivity and has been shown to contribute to the development of insulin resistance. In addition, GLUT2 has been implicated in the regulation of blood pressure and has been shown to be involved in the development of hypertension.

SLC26A3 has been shown to be involved in the regulation of glucose metabolism in various tissues and cells. For example, studies have shown that GLUT2 is involved in the uptake and storage of glucose in the liver, where it is a key protein in the regulation of insulin sensitivity and glucose metabolism. In addition, GLUT2 has been shown to be involved in the regulation of muscle glucose uptake and storage, which is important for maintaining muscle function during periods of starvation.

SLC26A3 has also been shown to be involved in the regulation of inflammation and has been implicated in the development of various inflammatory diseases. For example, studies have shown that GLUT2 is involved in the regulation of the production of pro-inflammatory cytokines, such as TNF-alpha, which are involved in the development of inflammatory diseases. In addition, GLUT2 has been shown to be involved in the regulation of the production of anti-inflammatory cytokines, such as IL-10, which are involved in the regulation of immune responses and have been implicated in the development of autoimmune diseases.

In addition to its involvement in glucose metabolism and inflammation, GLUT2 has also been shown to be involved in the regulation of other cellular processes that are important for maintaining cellular health and homeostasis. For example, GLUT2 has been shown to be involved in the regulation of cell adhesion, which is important for maintaining the integrity of tissues and is involved in the development of various diseases, including cancer. In addition, GLUT2 has been shown to be involved in the regulation of cell survival, which is important for maintaining the integrity of tissues and is involved in the development of various diseases, including neurodegenerative diseases.

SLC26A3 has also been shown to be involved in the regulation of sensory function, including vision and hearing. Studies have shown that GLUT2 is involved in the regulation of the transport of light-sensitive molecules to the retina and that it is involved in the regulation of the production of vision in the brain. In addition, GLUT2 has been shown to be involved in the regulation of auditory function and that it is involved in the regulation of the development of hearing in the inner ear.

In conclusion, SLC26A3 is a gene that encodes a protein involved in the regulation of glucose transport and metabolism. GLUT2 is a transmembrane protein that has been shown to play

Protein Name: Solute Carrier Family 26 Member 3

Functions: Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
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•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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