SLC29A2: A Potential Drug Target and Biomarker (G3177)

Target Name: SLC29A2

NCBI ID: G3177

SLC29A2

SLC29A2: A Potential Drug Target and Biomarker

Sodium-glucose cotransporter 2 (SLC29A2), also known as NST002363, is a member of the Sodium-glucose cotransporter (SGLT) family, which is a subfamily of nucleoside transporters (NRTs) that play a crucial role in the regulation of nucleoside transport and metabolism. SLC29A2 is expressed in most tissues and is involved in the transport of both sodium and glucose across the membrane of various cell types, including epithelial, endothelial, and mesenchymal tissues.

SLC29A2 has been identified as a potential drug target due to its involvement in various physiological processes, including cell signaling, neurotransmission, and insulin sensitivity. SLC29A2 has been shown to regulate a variety of cellular processes, including cell adhesion, migration, and the production of matrix-associated growth factors.

One of the most significant functions of SLC29A2 is its role in glucose metabolism. SLC29A2 is expressed in pancreatic beta cells, which are the primary producers of insulin in the body. SLC29A2 has been shown to regulate insulin secretion by interacting with the intracellular signaling pathway known as the TOR signaling pathway.

In addition to its role in insulin secretion, SLC29A2 has also been shown to play a critical role in maintaining normal glucose levels in the body. SLC29A2 has been shown to regulate glucose uptake and storage in muscle fibers, which is important for maintaining muscle mass and function.

SLC29A2 has also been shown to be involved in various signaling pathways that are important for cellular processes, including cell proliferation, migration, and angiogenesis. SLC29A2 has been shown to interact with a variety of intracellular signaling pathways, including the TOR signaling pathway, the PI3K/Akt signaling pathway, and the NF-kappa-B signaling pathway.

SLC29A2 has also been shown to be involved in the regulation of pain perception and neurotransmission. SLC29A2 has been shown to play a critical role in the production of pain signals, which are important for the regulation of pain perception. SLC29A2 has also been shown to be involved in the regulation of neurotransmission, including the production and release of neurotransmitters such as dopamine and GABA.

In conclusion, SLC29A2 is a well-established member of the Sodium-glucose cotransporter family that is involved in a variety of cellular processes, including cell signaling, neurotransmission, and insulin sensitivity. SLC29A2 has been identified as a potential drug target due to its involvement in various physiological processes and its role in the regulation of glucose metabolism, pain perception, and neurotransmission. Further research is needed to fully understand the role of SLC29A2 in cellular processes and its potential as a drug target.

Protein Name: Solute Carrier Family 29 Member 2

Functions: Mediates equilibrative transport of purine, pyrimidine nucleosides and the purine base hypoxanthine. Very less sensitive than SLC29A1 to inhibition by nitrobenzylthioinosine (NBMPR), dipyridamole, dilazep and draflazine

The "SLC29A2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC29A2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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