Target Name: SLC25A40
NCBI ID: G55972
Review Report on SLC25A40 Target / Biomarker Content of Review Report on SLC25A40 Target / Biomarker
SLC25A40
Other Name(s): Solute carrier family 25 member 40 | Probable mitochondrial glutathione transporter SLC25A40 | solute carrier family 25 member 40 | S2540_HUMAN | MCFP | mitochondrial carrier family protein | Mitochondrial carrier family protein

SLC25A40: A Potential Drug Target Or Biomarker

SLC25A40 is a member of the Solute Carrier Family 25, which is a well-established transmembrane protein family that plays a critical role in the regulation of intracellular signaling pathways. SLC25A40 has been identified as a potential drug target or biomarker due to its unique structure, function, and involvement in various diseases.

The SLC25A40 protein is a 40-kDa protein that is expressed in various tissues and cells, including brain, heart, skeletal muscles, and red blood cells. It is a member of the SLC25 family, which consists of 14 different proteins that share a conserved transmembrane domain and a unique catalytic domain. The SLC25 family is involved in the regulation of various intracellular signaling pathways, including signaling pathways related to cell adhesion, migration, and survival.

One of the unique features of SLC25A40 is its ability to form a cation-exchange complex with various ligands, including Na+, K+, and Ca2+. This ability is critical for its function in intracellular signaling pathways because it allows the protein to regulate the activity of Various intracellular signaling pathways, including the Na+/K+-ATPase, which is involved in the regulation of intracellular signaling pathways that are critical for cellular survival and growth.

SLC25A40 is also involved in the regulation of ion channels, including the potassium channel K channels. These channels play a critical role in the regulation of various physiological processes, including muscle contractions and heart rate. The regulation of these channels by SLC25A40 is critical for the proper function of these channels and is involved in the development and progression of various diseases, including heart disease and muscle disorders.

In addition to its involvement in intracellular signaling pathways, SLC25A40 is also involved in the regulation of various extracellular signaling pathways. For example, SLC25A40 is involved in the regulation of cell adhesion and migration, which are critical for the development and progression of various diseases, including cancer. The regulation of cell adhesion and migration by SLC25A40 is also involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

SLC25A40 is also involved in the regulation of various signaling pathways that are critical for cellular survival and growth. For example, SLC25A40 is involved in the regulation of the cell survival signaling pathway, which is critical for the development and progression of various diseases, including cancer. . The regulation of this pathway by SLC25A40 is also involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

SLC25A40 is also involved in the regulation of various signaling pathways that are critical for the development and progression of diseases, including diabetes. For example, SLC25A40 is involved in the regulation of the TGF-β signaling pathway, which is involved in the regulation of cellular growth and differentiation. The regulation of this pathway by SLC25A40 is also involved in the development and progression of diabetes, including the development of insulin resistance.

In conclusion, SLC25A40 is a unique protein that is involved in the regulation of various intracellular and extracellular signaling pathways that are critical for cellular survival and growth. Its ability to form a cation-exchange complex with various ligands and its involvement in the regulation of intracellular signaling pathways, including the Na+/K+-ATPase, ion channels, cell adhesion and migration, and signaling pathways related to cancer, neurodegenerative diseases, and diabetes make it an attractive drug target or biomarker. Further research is needed to fully understand the role of SLC25A40 in these diseases and to develop effective treatments.

Protein Name: Solute Carrier Family 25 Member 40

Functions: Probable mitochondrial transporter required for glutathione import into mitochondria (PubMed:34707288). Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles (PubMed:34707288). Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis (By similarity)

The "SLC25A40 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC25A40 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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