Target Name: SLC25A27
NCBI ID: G9481
Review Report on SLC25A27 Target / Biomarker Content of Review Report on SLC25A27 Target / Biomarker
SLC25A27
Other Name(s): RP11-446F17.2 | SLC25A27 variant 2 | Solute carrier family 25 member 27 | UCP4_HUMAN | Mitochondrial uncoupling protein 4 (isoform 2) | Mitochondrial uncoupling protein 4 (isoform 1) | Mitochondrial uncoupling protein 4 | SLC25A27 variant 1 | Solute carrier family 25 member 27, transcript variant 1 | Solute carrier family 25 member 27, transcript variant 2 | solute carrier family 25 member 27 | UCP4 | Uncoupling protein 4 | UCP 4 | uncoupling protein 4

SLC25A27: A Protein Regulating Blood Pressure and Other Processes

SLC25A27 (RP11-446F17.2) is a protein that is expressed in various tissues of the body, including the brain, heart, liver, and kidneys. It is a member of the SLC25 family of transport proteins, which are known for their ability to transport a wide variety of molecules across cell membranes. SLC25A27 has been shown to play a role in the regulation of blood pressure, and is often used as a drug target or biomarker for various diseases.

The SLC25 family of transport proteins consists of four subfamilies: SLC25A, SLC25B, SLC25C, and SLC25D. SLC25A27 is a member of the SLC25A subfamily, and is responsible for transporting the protein SLC25A27 across cell membranes. SLC25A27 is a 27 kDa protein that consists of 214 amino acid residues. It has a calculated pI of 10.9, which means that it is highly susceptible to changes in pH levels.

SLC25A27 has been shown to play a role in the regulation of blood pressure. High levels of SLC25A27 have been associated with an increased risk of hypertension, while low levels of SLC25A27 have been associated with a decreased risk of hypertension. This is because SLC25A27 is involved in the regulation of the volume of blood vessels, which is a critical factor in the regulation of blood pressure.

SLC25A27 has also been shown to play a role in the regulation of various other physiological processes in the body. For example, SLC25A27 has been shown to be involved in the regulation of inflammation, insulin sensitivity, and the production of reactive oxygen species (ROS).

SLC25A27 has also been shown to be a potential drug target or biomarker for various diseases. For example, studies have shown that SLC25A27 is downregulated in individuals with hypertension, and that inhibition of SLC25A27 has been shown to be effective in reducing blood pressure in these individuals. Additionally, SLC25A27 has been shown to be involved in the regulation of various signaling pathways, and may be a potential target for small molecules that can modulate these pathways.

In conclusion, SLC25A27 (RP11-446F17.2) is a protein that is involved in the regulation of various physiological processes in the body. It is a member of the SLC25 family of transport proteins, and has been shown to play a role in the regulation of blood pressure, as well as inflammation, insulin sensitivity, and other processes. As a result, SLC25A27 is often used as a drug target or biomarker for various diseases. Further research is needed to fully understand the role of SLC25A27 in the regulation of physiological processes and its potential as a drug.

Protein Name: Solute Carrier Family 25 Member 27

Functions: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat. May play a role in thermoregulatory heat production and metabolism in brain

The "SLC25A27 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC25A27 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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