SSC5D: A novel drug target and biomarker for cancer treatment

Target Name: SSC5D

NCBI ID: G284297

SSC5D

Other Name(s): Scavenger receptor cysteine rich family member with 5 domains, transcript variant 1 | Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (isoform 1) | SRCRL_HUMAN | SSc5D | Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D | scavenger receptor cysteine rich family member with 5 domains | Soluble scavenger protein with 5 SRCR domains | Scavenger receptor cysteine-rich glycoprotein | scavenger receptor cysteine rich domain containing (5 domains) | SSC5D variant 1 | scavenger receptor cysteine rich family, 5 domains | scavenger receptor cysteine-rich glycoprotein | soluble scavenger with 5 domains | S5D-SRCRB | soluble scavenger protein with 5 SRCR domains | Soluble scavenger with 5 domains

SSC5D: A novel drug target and biomarker for cancer treatment

Introduction

Scavenger receptor cysteine-rich family member with 5 domains (SSC5D) is a protein that plays a crucial role in various cellular processes. It is a member of the scavenger receptor family, which is known to be involved in cell signaling pathways, including cancer progression and metastasis. SSC5D has 5 domains, including an extracellular domain, a transmembrane domain, an intracellular domain, and a cytoplasmic domain.

Despite its significant involvement in cellular signaling pathways, SSC5D is not well understood, and its functions are still under investigation. However, recent studies have shown that SSC5D can be a potential drug target and biomarker for cancer treatment. In this article, we will explore the SSC5D protein, its functions, and its potential as a drug target.

Functional characterization of SSC5D

The SSC5D protein was first identified using gene expression studies and bioinformatics analysis. SSC5D is a 124-kDa protein that contains 5 domains: an N-terminal extracellular domain, a transmembrane domain, an A-type transmembrane domain, a B- type transmembrane domain, and a C-terminal cytoplasmic domain.

The extracellular domain of SSC5D contains a unique N-terminal region that is rich in cysteine 鈥嬧?媟esidues. This domain is involved in SSC5D's ability to interact with various signaling molecules, including tyrosine and src tyrosine kinases. The transmembrane domain of SSC5D is composed of 20 transmembrane 伪-helices, which is known to be involved in SSC5D's membrane interactions and its ability to interact with various signaling molecules.

The intracellular domain of SSC5D contains a unique C-terminal region that is involved in SSC5D's ability to interact with various intracellular signaling pathways, including the PI3K/Akt signaling pathway. SSC5D's ability to interact with various intracellular signaling pathways, including the ERK signaling pathway.

Potential drug targets and biomarkers for SSC5D

The unique functions of SSC5D make it an attractive drug target for cancer treatment. SSC5D has been shown to be involved in various cellular signaling pathways, including cancer progression and metastasis. Therefore, SSC5D may be a useful biomarker for cancer diagnosis and treatment.

One potential drug target for SSC5D is the PI3K/Akt signaling pathway. This pathway is involved in various cellular signaling pathways, including cell survival, angiogenesis, and inflammation. SSC5D has been shown to be involved in this pathway, and its inhibition has been shown to have anti-tumor effects in various cancer models. Therefore, SSC5D may be an effective inhibitor of the PI3K/Akt signaling pathway, and its use as a drug target may be an attractive approach for cancer treatment.

Another potential drug target for SSC5D is the ERK signaling pathway. This pathway is involved in various cellular signaling pathways, including cell growth, differentiation, and survival. SSC5D has been shown to be involved in this pathway, and its inhibition has been shown to have anti-tumor effects in various cancer models. Therefore, SSC5D may be an effective inhibitor of the ERK signaling pathway, and its use as a drug target may be an attractive approach for cancer treatment.

In addition to its potential as a drug target, SSC5D has also been shown to be a potential biomarker for cancer diagnosis and treatment. The unique functions of SSC5D make it an attractive marker for various types of cancer, including

Protein Name: Scavenger Receptor Cysteine Rich Family Member With 5 Domains

Functions: Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity)

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