STAG2: A Protein Regulator of Microtubules and Cell Division (G10735)

Target Name: STAG2

NCBI ID: G10735

STAG2

STAG2: A Protein Regulator of Microtubules and Cell Division

STAG2 (MKMS) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and muscle. It is a key regulator of the microtubules, which are the organizing structures that give cells their structure and keep them dividing. STAG2 has also been shown to play a role in a variety of diseases, including cancer, neurodegenerative diseases, and developmental disorders.

One of the main functions of STAG2 is to regulate the formation and stability of microtubules. Microtubules are made up of two types of protein: alpha-tubulin and beta-tubulin. alpha-tubulin is the major component of microtubules and is responsible for their stability. beta-tubulin helps to keep alpha-tubulin in place and is the protein that is targeted by the drug tau, which is associated with the development of Alzheimer's disease.

STAG2 has been shown to regulate the assembly and disassembly of microtubules. This means that it helps to ensure that microtubules are properly formed and that they are able to do their job of organizing and moving cells. One of the things that STAG2 does to help with this is to prevent the formation of aberrant microtubules. Abnormal microtubules can cause cells to behave abnormally and can contribute to a variety of diseases.

STAG2 has also been shown to play a role in the regulation of cell division. In fact, STAG2 is highly expressed in tissues that are actively dividing, such as the brain and the liver. This suggests that it plays a key role in the regulation of cell division and that it may be a useful target for drugs that are designed to stop the progression of cancer.

In addition to its role in cell division, STAG2 has also been shown to be involved in a variety of other processes that are important for the proper functioning of cells. For example, STAG2 has been shown to play a role in the regulation of the immune system, the nervous system, and the endocrine system. It also has been shown to be involved in the regulation of the blood-brain barrier, which is a barrier that helps to protect the brain from harmful substances that could enter it.

One of the challenges in studying STAG2 is that it is a very complex protein and there are many different ways that it can be involved in the regulation of microtubules and cell division. This makes it difficult to understand exactly how STAG2 works and to identify potential drug targets. However, studies have shown that STAG2 is involved in a variety of processes that are important for the proper functioning of cells and that it may be a useful target for drugs that are designed to stop the progression of cancer or other diseases.

In conclusion, STAG2 is a protein that is expressed in a variety of tissues throughout the body and is involved in a number of important processes that help to keep cells dividing and organized. While more research is needed to fully understand how STAG2 works, it is clear that it is a potential drug target and may be a useful target for a variety of diseases.

Protein Name: Stromal Antigen 2

Functions: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis

The "STAG2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about STAG2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets