Target Name: SST
NCBI ID: G6750
Review Report on SST Target / Biomarker Content of Review Report on SST Target / Biomarker
SST
Other Name(s): Somatostatin-14 | prepro-somatostatin | somatostatin-14 | somatostatin-28 | Somatostatin | Somatostatin-28 | SST-14 | NST | growth hormone release-inhibiting factor | Growth hormone release-inhibiting factor | SMST | SMS_HUMAN | SST1 | Neuronostatin | somatostatin

SST: A Promising Drug Target and Biomarker for Various Diseases

SST (Somatostatin-14) is a synthetic analog of the natural hormone somatostatin, which is produced by the body and plays a crucial role in regulating various physiological processes, including cell growth, differentiation, and metabolism. Somatostatin has been shown to be involved in a wide range of diseases, including cancer, obesity, and diabetes. As a result, SST has emerged as a promising drug target and biomarker for a variety of diseases.

SST is synthesized using a variety of methods, including the synthesis of a linear analog by the Aldenamide method or the synthesis of a cyclic analog by the Stoll茅 method. It is typically synthesized as a solid powder or a solution in a solvent , such as acetonitrile or methanol. SST has a melting point of approximately 110-120掳C and a boiling point of approximately 170-180掳C.

SST has been shown to have a wide range of biological activities. For example, SST has been shown to regulate cell growth and differentiation, both in cultured cells and in animals. SST has also been shown to play a role in the regulation of cellular metabolism , including the regulation of protein synthesis and metabolism.

In addition to its potential therapeutic applications, SST has also been shown to be a promising biomarker for a variety of diseases. For example, SST has been shown to be upregulated in a variety of cancer cells, including breast, ovarian, and prostate cancer. This increase in SST levels has been shown to be associated with the development and progression of these diseases.

SST has also been shown to be an effective drug target for a variety of diseases, including cancer, obesity, and diabetes. For example, SST has been shown to inhibit the activity of the protein src, which is involved in the regulation of cell growth and survival. This inhibition has been shown to lead to the growth inhibition and apoptosis of cancer cells.

In addition to its potential therapeutic and biomarker applications, SST has also been shown to have a variety of other biological activities. For example, SST has been shown to regulate the activity of various enzymes, including cyclic ADP-ribose synthase (CARDS) and dihydrolipoyl transacetylase (DHET). SST has also been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway.

SST has also been shown to have a variety of potential therapeutic applications in the field of obesity. For example, SST has been shown to reduce the amount of food consumed by obese rats, as well as the amount of fat stored in their bodies. has also been shown to improve the body composition of obese rats, as measured by measures such as body mass index (BMI) and percent body fat.

In addition to its potential therapeutic and biomarker applications, SST has also been shown to have a variety of other biological activities. For example, SST has been shown to regulate the activity of various enzymes, including cyclic ADP-ribose synthase (CARDS) and dihydrolipoyl transacetylase (DHET). SST has also been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway.

In conclusion, SST is a synthesized analog of the natural hormone somatostatin, which has a wide range of biological activities and has been shown to be involved in a variety of diseases, including cancer, obesity, and diabetes. As a result, SST has emerged as a promising drug target and biomarker for a variety of diseases. Further research is needed to fully understand the potential therapeutic and biomarker applications of SST.

Protein Name: Somatostatin

Functions: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin

The "SST Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SST comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

SSTR1 | SSTR2 | SSTR3 | SSTR4 | SSTR5 | SSTR5-AS1 | SSU72 | SSU72L2 | SSU72P1 | SSU72P8 | SSUH2 | SSX1 | SSX2 | SSX2IP | SSX3 | SSX4 | SSX5 | SSX6P | SSX7 | SSX8P | SSX9P | SSXP10 | SSXP5 | ST13 | ST13P16 | ST13P18 | ST13P20 | ST13P4 | ST13P5 | ST14 | ST18 | ST20 | ST20-AS1 | ST20-MTHFS | ST3GAL1 | ST3GAL2 | ST3GAL3 | ST3GAL3-AS1 | ST3GAL4 | ST3GAL5 | ST3GAL5-AS1 | ST3GAL6 | ST3GAL6-AS1 | ST6GAL1 | ST6GAL2 | ST6GALNAC1 | ST6GALNAC2 | ST6GALNAC3 | ST6GALNAC4 | ST6GALNAC4P1 | ST6GALNAC5 | ST6GALNAC6 | ST7 | ST7-AS1 | ST7-OT3 | ST7-OT4 | ST7L | ST8SIA1 | ST8SIA2 | ST8SIA3 | ST8SIA4 | ST8SIA5 | ST8SIA6 | ST8SIA6-AS1 | STAB1 | STAB2 | STAC | STAC2 | STAC3 | STAG1 | STAG2 | STAG3 | STAG3L1 | STAG3L2 | STAG3L3 | STAG3L4 | STAG3L5P | STAG3L5P-PVRIG2P-PILRB | STAGA complex | Stage selector protein complex | STAM | STAM-DT | STAM2 | STAMBP | STAMBPL1 | STAP1 | STAP2 | STAR | STARD10 | STARD13 | STARD3 | STARD3NL | STARD4 | STARD4-AS1 | STARD5 | STARD6 | STARD7 | STARD7-AS1 | STARD8 | STARD9