Target Name: ST8SIA2
NCBI ID: G8128
Review Report on ST8SIA2 Target / Biomarker Content of Review Report on ST8SIA2 Target / Biomarker
ST8SIA2
Other Name(s): STX | HsT19690 | Sialyltransferase 8 (alpha-2, 8-sialytransferase) B | SIAT8-B | Alpha-2,8-sialyltransferase 8B (isoform 1) | ST8SIA2 variant 1 | ST8SiaII | Sialyltransferase St8Sia II | sialyltransferase St8Sia II | ST8SIA-II | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | Sialytransferase St8Sia II | sialyltransferase 8 (alpha-2, 8-sialytransferase) B | SIA8B_HUMAN | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2, transcript variant 1 | sialyltransferase X | alpha-2,8-sialyltransferase 8B 1 | Sialyltransferase 8B | SIAT8B | sialyltransferase 8B | ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 2 | Sialyltransferase X | Alpha-2,8-sialyltransferase 8B

ST8SIA2: A Potential Drug Target and Biomarker

Stem cells are a crucial part of our bodies, as they are the foundation of our tissues and organs. They are able to develop into any type of cell in the body, making them a powerful tool for regeneration and tissue repair. However, stem cells have a limited lifespan and are often harvested from the body, which can be a risky and often ineffective process.

Recent studies have suggested that one potential solution to this problem could be to target the ST8SIA2 protein. ST8SIA2 is a protein that is expressed in stem cells and has been shown to play a role in the development and maintenance of these cells.

Targeting ST8SIA2: A Potential Drug Pathway

The drug pipeline for targeting ST8SIA2 is still in its early stages, but it holds great promise as a potential treatment for a variety of diseases.

One of the most promising targets for ST8SIA2 is the use of small molecules, which can be used to inhibit the activity of the protein. Researchers have identified a number of small molecules that have been shown to interact with ST8SIA2 and have the potential to be used as drug candidates.

One of the most promising of these small molecules is called NEDD8, which is a non-coding RNA molecule that has been shown to interact with ST8SIA2. NEDD8 has been shown to play a role in the regulation of stem cell proliferation and has the potential to be used as a therapeutic agent.

Another small molecule that has been shown to interact with ST8SIA2 is called HSP70, which is a protein that is involved in the regulation of protein synthesis and may be able to interact with ST8SIA2 to influence its activity.

In addition to these small molecules, researchers have also identified a number of other potential drug targets that may interact with ST8SIA2. These include proteins that are involved in cell adhesion, migration, and the regulation of the immune response.

Measuring the Effectiveness of ST8SIA2 Interference: Experimentation

To determine the effectiveness of ST8SIA2 interference, researchers have used a variety of techniques to measure the activity of the protein. These include in vitro assays, such as cell culture and protein extraction, as well as in vivo assays, such as animal models of disease.

One of the most promising forms of ST8SIA2 interference is the use of small molecules that have been shown to interact with the protein. These small molecules have been shown to reduce the activity of ST8SIA2 and to inhibit its development in stem cells.

In vitro assays have shown that the small molecules used to inhibit ST8SIA2 activity have the potential to be effective in reducing the growth of cancer cells and the development of new tumors. In addition, in vivo assays have shown that these small molecules have the potential to be effective in preventing the development of cancer in animal models.

Conclusion

ST8SIA2 is a protein that has been shown to play a crucial role in the development and maintenance of stem cells. In addition, it has the potential to be a drug target and biomarker for a variety of diseases. recent studies have shown that small molecules such as NEDD8 and HSP70 have the potential to be effective in inhibiting the activity of ST8SIA2 and may be used as therapeutic agents. Further research is needed to fully understand the effects of ST8SIA2 interference and to determine its potential as a drug target and biomarker.

Protein Name: ST8 Alpha-N-acetyl-neuraminide Alpha-2,8-sialyltransferase 2

Functions: May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression

The "ST8SIA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ST8SIA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

ST8SIA3 | ST8SIA4 | ST8SIA5 | ST8SIA6 | ST8SIA6-AS1 | STAB1 | STAB2 | STAC | STAC2 | STAC3 | STAG1 | STAG2 | STAG3 | STAG3L1 | STAG3L2 | STAG3L3 | STAG3L4 | STAG3L5P | STAG3L5P-PVRIG2P-PILRB | STAGA complex | Stage selector protein complex | STAM | STAM-DT | STAM2 | STAMBP | STAMBPL1 | STAP1 | STAP2 | STAR | STARD10 | STARD13 | STARD3 | STARD3NL | STARD4 | STARD4-AS1 | STARD5 | STARD6 | STARD7 | STARD7-AS1 | STARD8 | STARD9 | STARP1 | STAT1 | STAT2 | STAT3 | STAT4 | STAT4-AS1 | STAT5 | STAT5A | STAT5B | STAT6 | STATH | STAU1 | STAU2 | STAU2-AS1 | STBD1 | STC1 | STC2 | STEAP1 | STEAP1B | STEAP2 | STEAP2-AS1 | STEAP3 | STEAP3-AS1 | STEAP4 | STEEP1 | Steroid 5-alpha-Reductase | Sterol O-acyltransferase (ACAT) | Sterol Regulatory Element-Binding Protein | STH | STIL | STIM1 | STIM2 | STIMATE | STIN2-VNTR | STING1 | STIP1 | STK10 | STK11 | STK11IP | STK16 | STK17A | STK17B | STK19 | STK24 | STK25 | STK26 | STK3 | STK31 | STK32A | STK32A-AS1 | STK32B | STK32C | STK33 | STK35 | STK36 | STK38 | STK38L | STK39 | STK4