Target Name: UBN1
NCBI ID: G29855
Review Report on UBN1 Target / Biomarker Content of Review Report on UBN1 Target / Biomarker
UBN1
Other Name(s): UBN1 variant 2 | Protein VT4 | Ubinuclein-1 | HIRA-binding protein | UBN1_HUMAN | Ubinuclein 1, transcript variant 2 | Ubinuclein-1 (isoform a) | VT | Ubiquitously expressed nuclear protein | VT4 | ubiquitously expressed nuclear protein | ubinuclein 1

Unlocking The Potential of UBN1: A Protein with Multiple Therapeutic Applications

UBN1 (UBN1 variant 2) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and kidneys. It is a member of the UBQU 1 family, which includes a variety of genes that encode for proteins involved in the uptake and transportation of various nutrients and substances throughout the body.

One of the unique aspects of UBN1 is its ability to interact with a variety of different molecules, including transcription factors, signaling proteins, and metabolic enzymes. This interacting ability makes UBN1 an important player in a variety of cellular processes, including cell signaling, metabolism, and stress response.

In addition to its role in cellular signaling, UBN1 has also been shown to play a potential role as a drug target. Several studies have suggested that UBN1 may be a potential target for small molecule inhibitors, with potential therapeutic applications in a range of diseases, including cancer, neurodegenerative diseases, and cardiovascular disease.

One of the reasons for the interest in UBN1 as a drug target is its involvement in a variety of cellular processes that are often disrupted in these diseases. For example, UBN1 has been shown to be involved in the regulation of cell signaling pathways that are often disrupted in cancer, such as the PI3K/Akt signaling pathway. This pathway is involved in the regulation of cell growth, survival, and angiogenesis, and has been implicated in the development and progression of many different types of cancer.

In addition to its involvement in cancer, UBN1 has also been shown to be involved in the regulation of other cellular processes that are often disrupted in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. These diseases are characterized by the progressive loss of brain cells and the development of neurofibrillary tangles, which are thought to contribute to the symptoms and progression of these diseases.

Another potential reason for the interest in UBN1 as a drug target is its involvement in the regulation of cellular stress response. UBN1 has been shown to play a role in the regulation of cellular stress responses, including the response to oxidative stress and inflammation. This is important because the regulation of cellular stress responses is often disrupted in many neurodegenerative diseases, and these disruptions may contribute to the development and progression of these diseases.

In addition to its potential role as a drug target, UBN1 also has several potential therapeutic applications in other areas. For example, it has been shown to have potential anti-inflammatory effects, and may be a useful target for the treatment of chronic inflammatory disorders. UBN1 has also been shown to have potential anti-cancer effects, and may be a useful target for the treatment of various types of cancer.

Overall, UBN1 is an important protein that has the potential to be a drug target for a variety of diseases. Further research is needed to fully understand the role of UBN1 in cellular processes and its potential therapeutic applications.

Protein Name: Ubinuclein 1

Functions: Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly

The "UBN1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about UBN1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

UBN2 | UBOX5 | UBOX5-AS1 | UBP1 | UBQLN1 | UBQLN1-AS1 | UBQLN2 | UBQLN3 | UBQLN4 | UBQLNL | UBR1 | UBR2 | UBR3 | UBR4 | UBR5 | UBR5-DT | UBR7 | UBTD1 | UBTD2 | UBTF | UBTFL1 | UBTFL2 | UBTFL6 | UBXN1 | UBXN10 | UBXN11 | UBXN2A | UBXN2B | UBXN4 | UBXN6 | UBXN7 | UBXN8 | UCA1 | UCHL1 | UCHL1-DT | UCHL3 | UCHL5 | UCK1 | UCK2 | UCKL1 | UCKL1-AS1 | UCMA | UCN | UCN2 | UCN3 | UCP1 | UCP2 | UCP3 | UDP-Glycosyltransferase | UDP-N-Acetylglucosamine--Peptide N-Acetylglucosaminyltransferase (O-GlcNAc Transferase) | UEVLD | UFC1 | UFD1 | UFD1-AS1 | UFL1 | UFM1 | UFSP1 | UFSP2 | UGCG | UGDH | UGDH-AS1 | UGGT1 | UGGT2 | UGP2 | UGT1A1 | UGT1A10 | UGT1A3 | UGT1A4 | UGT1A5 | UGT1A6 | UGT1A7 | UGT1A8 | UGT1A9 | UGT2A1 | UGT2A2 | UGT2A3 | UGT2B10 | UGT2B11 | UGT2B15 | UGT2B17 | UGT2B27P | UGT2B28 | UGT2B29P | UGT2B4 | UGT2B7 | UGT3A1 | UGT3A2 | UGT8 | UHMK1 | UHRF1 | UHRF2 | UICLM | UIMC1 | ULBP1 | ULBP2 | ULBP3 | ULK1 | ULK2 | ULK3 | ULK4