Target Name: APOL3
NCBI ID: G80833
Review Report on APOL3 Target / Biomarker Content of Review Report on APOL3 Target / Biomarker
APOL3
Other Name(s): APOL3 variant alpha/d | CG12-1 | apolipoprotein L3 | apolipoprotein L-III splice variant beta | apolipoprotein L-III splice variant alpha | Apolipoprotein L3 (isoform 1) | APOL3 variant beta/a | Apolipoprotein L3 | CG121 | APOL3_HUMAN | apoL-III | APOLIII | Apolipoprotein L-III | ApoL-III | apolipoprotein L, 3 | TNF-inducible protein CG12-1 | apolipoprotein L-III | Apolipoprotein L3, transcript variant alpha/d | Apolipoprotein L3 (isoform 3) | Apolipoprotein L3, transcript variant beta/a | CG12_1

APOL3: Plasma Membrane Transient Subunit and Angiogenesis

APOL3 (Alpha-3 subunit of the Plasma Membrane Transient pore protein) is a protein that is expressed in various cell types of the human body, including epithelial, endothelial, and nervous cells. It is a member of the family of transmembrane proteins, which are involved in the regulation of cell-cell and cell-extracellular signaling.

The Alpha-3 subunit of Plasma Membrane Transient (PMT) is a type of protein that is involved in the regulation of ion and water transport across the cell membrane. It is composed of two transmembrane domains, an N-terminus domain that is involved in the formation of the transmembrane region and a C-terminus domain that is involved in the formation of the cytoplasmic region.

The N-terminus domain of APOL3 is composed of a single transmembrane segment that is involved in the formation of the transmembrane region. This segment contains a unique fusion of two conserved amino acid residues, which is known as the \"alpha-beta\" structure. This structure is thought to play a role in the stability and flexibility of the N-terminus domain.

The C-terminus domain of APOL3 is composed of a unique transmembrane region that is involved in the formation of the cytoplasmic region. This region contains a conserved glycine residue at its N-terminus, as well as a unique amino acid sequence that is located between these two residues. The C-terminus domain also contains a transmembrane region that is involved in the formation of the cytoplasmic region.

APOL3 is involved in the regulation of a wide range of cellular processes, including cell signaling, ion and water transport, and cell adhesion. It is thought to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed in response to the needs of the body.

One of the key functions of APOL3 is its role in the regulation of angiogenesis. It is thought to play a key role in the formation of blood vessels in the placenta, which is the organ that provides oxygen and nutrients to the developing fetus.

In addition to its role in angiogenesis, APOL3 is also involved in the regulation of cell signaling. It is thought to play a role in the regulation of T cell signaling, which is the process by which T cells are able to recognize and respond to the presence of foreign substances in the body.

APOL3 is also involved in the regulation of ions and water transport. It is thought to play a role in the regulation of the movement of ions and water molecules across the cell membrane, which is important for the proper functioning of many cellular processes.

In conclusion, APOL3 is a protein that is involved in the regulation of a wide range of cellular processes, including cell signaling, ion and water transport, and cell adhesion. It is a member of the family of transmembrane proteins, and its unique N- terminus and C-terminus domains are thought to play a key role in its function. As a drug target or biomarker, APOL3 may be a valuable target for the development of new therapies for a variety of diseases.

Protein Name: Apolipoprotein L3

Functions: May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles

The "APOL3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about APOL3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

APOL4 | APOL5 | APOL6 | APOLD1 | Apolipoprotein B mRNA editing complex | APOM | APOO | APOOL | APOOP2 | APOOP5 | APP | APPAT | APPBP2 | APPL1 | APPL2 | APRG1 | APRT | APTR | APTX | AQP1 | AQP10 | AQP11 | AQP12A | AQP12B | AQP2 | AQP3 | AQP4 | AQP4-AS1 | AQP5 | AQP6 | AQP7 | AQP7P1 | AQP7P2 | AQP7P3 | AQP7P5 | AQP8 | AQP9 | AQR | AR | ARAF | ARAP1 | ARAP1-AS2 | ARAP2 | ARAP3 | ARC | ARCN1 | AREG | AREL1 | ARF1 | ARF3 | ARF4 | ARF5 | ARF6 | ARFGAP1 | ARFGAP2 | ARFGAP3 | ARFGEF1 | ARFGEF2 | ARFGEF3 | ARFIP1 | ARFIP2 | ARFRP1 | ARG1 | ARG2 | ARGFX | ARGFXP2 | Arginase | ARGLU1 | ARHGAP1 | ARHGAP10 | ARHGAP11A | ARHGAP11A-DT | ARHGAP11B | ARHGAP12 | ARHGAP15 | ARHGAP17 | ARHGAP18 | ARHGAP19 | ARHGAP19-SLIT1 | ARHGAP20 | ARHGAP21 | ARHGAP22 | ARHGAP22-IT1 | ARHGAP23 | ARHGAP24 | ARHGAP25 | ARHGAP26 | ARHGAP26-AS1 | ARHGAP26-IT1 | ARHGAP27 | ARHGAP27P1 | ARHGAP27P1-BPTFP1-KPNA2P3 | ARHGAP27P2 | ARHGAP28 | ARHGAP29 | ARHGAP30 | ARHGAP31 | ARHGAP31-AS1 | ARHGAP32 | ARHGAP33