HMOX1: A Protein Targeted for Cancer and Neurodegenerative Diseases

Target Name: HMOX1

NCBI ID: G3162

HMOX1

HMOX1: A Protein Targeted for Cancer and Neurodegenerative Diseases

HMOX1 (bK286B10) is a protein that is expressed in various tissues throughout the body, including the brain, lungs, heart, kidneys, and gastrointestinal tract. It is a key regulator of cell growth and differentiation, and is involved in the development and maintenance of tissues and organs.

HMOX1 has been identified as a potential drug target due to its involvement in a variety of physiological processes that are important for human health. For example, HMOX1 has been shown to play a role in the development and progression of various types of cancer, including neuro cancer. It has also been linked to a number of diseases, including cardiovascular disease and respiratory failure.

In addition to its potential as a drug target, HMOX1 has also been identified as a potential biomarker for a variety of diseases. For example, studies have shown that HMOX1 levels are elevated in individuals with neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, higher HMOX1 levels have been associated with an increased risk of certain types of cancer, such as lung cancer.

The potential benefits of targeting HMOX1 with drugs or other therapeutic agents are significant. If successful, these treatments could provide new treatments for a variety of diseases that are currently difficult to treat, or have a high risk of side effects. Additionally, by understanding the underlying mechanisms of HMOX1's role in various physiological processes, researchers may be able to develop new insights into how cells and tissues function, and how they can be targeted to treat a variety of diseases.

Overall, HMOX1 is a protein that has the potential to be a drug target or biomarker, and research into its role in various physiological processes and its potential as a therapeutic agent is an important area of study. Further research is needed to fully understand its role and potential as a drug target, and to develop effective treatments for diseases that are currently difficult to treat.

Protein Name: Heme Oxygenase 1

Functions: Catalyzes the oxidative cleavage of heme at the alpha-methene bridge carbon, released as carbon monoxide (CO), to generate biliverdin IXalpha, while releasing the central heme iron chelate as ferrous iron (PubMed:7703255, PubMed:11121422). Affords protection against programmed cell death and this cytoprotective effect relies on its ability to catabolize free heme and prevent it from sensitizing cells to undergo apoptosis (PubMed:20055707)

The "HMOX1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HMOX1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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