LANCL3: A Promising Protein for Drug Targets and Biomarkers (G347404)

Target Name: LANCL3

NCBI ID: G347404

LANCL3

LANCL3: A Promising Protein for Drug Targets and Biomarkers

LANCL3 (LANC3_HUMAN) is a protein that is expressed in various tissues of the human body, including the lungs, heart, kidneys, and brain. It is a member of the Orchidaceae family of proteins, which are a diverse superfamily of transmembrane and cytoplasmic proteins that play a critical role in various cellular processes.

LANCL3 is characterized by its unique structure and biology. It is a 120-kDa protein that consists of a 48-kDa catalytic domain and a 72-kDa transmembrane region. The catalytic domain is responsible for the protein's unique catalytic activity, which allows it to catalyze the reversible addition of the reactive groups, such as aldehydes and amides, to the carbonyl group of the target molecule.

The transmembrane region of LANCL3 is made up of a single transmembrane 伪-helical structure. It is characterized by the presence of a unique positively charged amino acid residue, known as EGYT, which is involved in the regulation of the protein's stability and functions.

LANCL3 is involved in various physiological processes in the human body, including the regulation of inflammation, stress responses, and cellular signaling pathways. It is also a potential drug target and biomarker for various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.

One of the most promising aspects of LANCL3 is its potential as a drug target. The unique catalytic activity of LANCL3 makes it an attractive target for small molecules that can modulate its activity. Several studies have shown that LANCL3 is highly sensitive to small molecules, including inhibitors of the enzyme tyrosine aminotransferase (TAT), which is involved in the regulation of cellular signaling pathways.

LANCL3 has also been shown to be involved in various stress responses, including the regulation of inflammation and cellular signaling pathways. It is involved in the regulation of the cytokine profile, which is critical for the regulation of inflammation and cellular stress responses.

Another promising aspect of LANCL3 is its potential as a biomarker for various diseases. The expression of LANCL3 is regulated by various factors, including cytokines, chemokines, and signaling pathways. Therefore, the expression of LANCL3 can be used as a marker for various diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.

In conclusion, LANCL3 is a unique and promising protein that is involved in various physiological processes in the human body. Its catalytic activity and transmembrane structure make it an attractive target for small molecules, and its involvement in various stress responses and diseases make it a potential biomarker. Further research is needed to fully understand the role of LANCL3 in the regulation of cellular processes and its potential as a drug target and biomarker for various diseases.

Protein Name: LanC Like Family Member 3

The "LANCL3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LANCL3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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