Target Name: ARMS2
NCBI ID: G387715
Review Report on ARMS2 Target / Biomarker Content of Review Report on ARMS2 Target / Biomarker
ARMS2
Other Name(s): age-related maculopathy susceptibility 2 | LOC387715 | ARMD8 | Age-related maculopathy susceptibility protein 2 | Gene LOC387715 | Age-related maculopathy susceptibility 2 | ARMS2_HUMAN | Hypothetical protein LOC387715

ARMS2: A Protein Involved in The Development and Progression of Age-Related Maculopathy

Age-related maculopathy (ARM) is a progressive sight-threatening disorder that affects the macula, a part of the retina responsible for our central vision, and is a leading cause of blindness in the developed world. The macula is the area of 鈥嬧?媡he retina responsible for our ability to see fine details and read words, and it is made up of a network of blood vessels that supply it with oxygen and nutrients. As we age, the blood vessels inside the macula can become narrowed or blocked, leading to a buildup of waste material and a reduction in the flow of oxygen and nutrients to the macula. This can cause the macula to break down and lead to blindness.

ARMS2 is a protein that is expressed in the retina and is associated with the development and progression of ARM. It is a key regulator of the blood flow to the retina and has been shown to play a role in the development of ARM.

The Role of ARMS2 in ARM Development

ARMS2 is a transmembrane protein that is located in the retina. It is composed of four distinct subunits that are held together by disulfide bonds. The subunits of ARMS2 are involved in various cellular processes that are necessary for the development and progression of ARM.

One of the subunits of ARMS2 is called ARMS2-1. This subunit is involved in the regulation of the blood flow to the retina. It does this by controlling the movement of blood vessels that supply the retina. By doing so, it ensures that the The retina receives a supply of oxygen and nutrients that is necessary for the healthy functioning of the retina.

Another subunit of ARMS2 is called ARMS2-2. This subunit is involved in the regulation of the growth and differentiation of photoreceptor cells. These cells are responsible for transmitting information about the light that we see to the brain, and they require a constant supply of oxygen and nutrients in order to function properly.

The Role of ARMS2 in ARM Progression

ARMS2 is also involved in the regulation of the progression of ARM. Studies have shown that higher levels of ARMS2 are associated with a greater risk of developing ARM. Additionally, studies have shown that ARMS2 is involved in the progression of ARM by regulating the production of waste material that accumulates in the retina.

In addition to its role in the regulation of waste material, ARMS2 is also involved in the regulation of the immune response. Studies have shown that ARMS2 is involved in the regulation of the immune response that occurs in the retina, and that it plays a role in protecting the retina from damage caused by the immune system.

The Potential Role of ARMS2 as a Drug Target

The potential role of ARMS2 as a drug target is an area of 鈥嬧?媜ngoing research. Studies have shown that ARMS2 is involved in the development and progression of ARM, and that it plays a role in regulating the immune response that occurs in the retina. This suggests that ARMS2 may be an attractive target for new therapies for ARM.

One potential approach to targeting ARMS2 is to use small molecules that can inhibit its activity. Researchers have identified a number of small molecules that have been shown to inhibit the activity of ARMS2 and have used these molecules to test their effectiveness in treating ARM. Some of these molecules have been shown to be effective in animal models of ARM.

Another potential approach to targeting ARMS2 is to use antibodies that can specifically bind to AR

Protein Name: Age-related Maculopathy Susceptibility 2

The "ARMS2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ARMS2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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