MIR143: A Potential Drug Target and Biomarker (G406935)
MIR143: A Potential Drug Target and Biomarker
MIR143 (hsa-miR-143-3p) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. Its unique structure and function have made it an attractive target for researchers to study, and several studies have investigated its potential implications for human health.
MIR143 is a microRNA (miRNA) that is derived from the mouse insulin gene. It is a small non-coding RNA molecule that contains 199 amino acid residues and has a calculated molecular weight of 20.9 kDa. MIR143 is expressed in various tissues and cells in the body and has been shown to play a role in various biological processes, including cell growth, differentiation, and apoptosis.
One of the key features of MIR143 is its ability to interact with other molecules and proteins. It has been shown to interact with several protein partners, including the transcription factor, p53, and the protein, heat shock protein (Hsp) A1. These interactions have important implications for the function of MIR143 and may be potential drug targets or biomarkers.
MIR143 has also been shown to play a role in several diseases, including cancer. Several studies have shown that MIR143 is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. This overexpression is associated with poor prognosis and increased risk of disease.
In addition to its potential as a drug target or biomarker, MIR143 is also of interest to researchers because of its unique structure and function. Its amino acid sequence is highly conserved between different species, which suggests that it has a universal function. This conservation suggests that MIR143 may be a good candidate for drug targeting or biomarking in various diseases.
MIR143 has also been shown to have potential clinical applications. Several studies have shown that MIR143 can be used as a therapeutic agent to treat various diseases, including cancer. For example, a study published in the journal PLoS One found that MIR143 can be used to inhibit the growth of cancer cells in a variety of formats, including cell lines and animal models. Another study published in the journal Oncology Reports found that MIR143 can be used to treat colorectal cancer by inhibiting the activity of a protein that promotes cell growth.
In conclusion, MIR143 is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and function, as well as its potential clinical applications, make it an attractive target for researchers to study. Further research is needed to fully understand the function of MIR143 and its potential as a drug or biomarker.
Protein Name: MicroRNA 143
The "MIR143 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR143 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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