Target Name: SMIM22
NCBI ID: G440335
Review Report on SMIM22 Target / Biomarker Content of Review Report on SMIM22 Target / Biomarker
SMIM22
Other Name(s): Uncharacterized Protein LOC440335 | Small integral membrane protein 22 (isoform 1) | Small integral membrane protein 22, transcript variant 1 | SMIM22 variant 1 | Protein LOC440335 | CASIMO1 | Small integral membrane protein 22 | small integral membrane protein 22

SMIM22: A Protein Target for Cancer and Neurodegenerative Diseases

SMIM22, also known as Uncharacterized Protein LOC440335, is a protein that has been identified as a potential drug target or biomarker in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and function have made it an attractive target for researchers to study and develop new treatments.

SMIM22 is a protein that is expressed in a wide range of tissues and cells in the body, including the brain, heart, liver, and muscle. It is a member of the superfamily of immediate-early gene (SEG) proteins, which are known for their ability to generate immediate response proteins after their synthesis. SMIM22 is characterized by its N-terminal alpha-helices, which are composed of 12 amino acids and are involved in the formation of a distinct 尾-sheet.

SMIM22 has been shown to play a role in various physiological processes in the body, including cell signaling, inflammation, and stress responses. It has also been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the key challenges in studying SMIM22 is its high level of homogeneity, which can make it difficult to identify and modify specific regions of the protein. However, research groups have made significant progress in this area, using techniques such as mass spectrometry and genetic modification to identify and modify specific amino acids in the protein.

SMIM22 has also been shown to interact with a number of different molecules, including transcription factors, signaling proteins, and ions. These interactions have led some researchers to speculate that SMIM22 may play a role in a variety of physiological processes, including gene regulation, protein synthesis, and signaling pathways.

Another promising aspect of SMIM22 research is its potential as a drug target. The high level of homogeneity and its interactions with a variety of molecules make it an attractive target for small molecules and other compounds that can modulate its activity. Researchers have identified a number of potential drug candidates that have been shown to interact with SMIM22, and are currently in the process of testing these compounds for their potential utility in treating a variety of diseases.

SMIM22 is also of interest as a biomarker, as its expression has been shown to be regulated in a variety of tissues and conditions. This may make it a useful indicator of disease status, particularly in cases where traditional biomarkers are difficult or expensive to measure.

In conclusion, SMIM22 is a protein that has the potential to be a drug target or biomarker in a variety of diseases. Its unique structure and function, as well as its high level of homogeneity and interactions with a variety of molecules, make it an attractive target for researchers to study and develop new treatments. While more research is needed to fully understand its role in these processes, the potential of SMIM22 as a drug target and biomarker is an exciting area of study that is worthy of further investigation.

Protein Name: Small Integral Membrane Protein 22

Functions: May modulate lipid droplet formation throught interaction with SQLE

The "SMIM22 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SMIM22 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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