Target Name: SMIM6
NCBI ID: G100130933
Review Report on SMIM6 Target / Biomarker Content of Review Report on SMIM6 Target / Biomarker
SMIM6
Other Name(s): ELN | SMIM6_HUMAN | endoregulin | Small integral membrane protein 6 | C17orf110 | small integral membrane protein 6

SMIM6: A Potential Drug Target and Biomarker

SMIM6, or Sodium-Glucose Indicator M6, is a protein that is expressed in various tissues and cells in the body. It is a key regulator of the glucose homeostasis and has been implicated in a wide range of physiological processes, including metabolism, inflammation, and neurodegeneration. In recent years, researchers have been increasingly interested in SMIM6 as a potential drug target and biomarker for a variety of diseases, including diabetes, cancer, and neurodegenerative disorders.

SMIM6 functions as a glucose sensor, constantly monitoring the levels of glucose in the body and signaling this information to downstream signaling pathways. It is a key regulator of the insulin/IGF-1 signaling pathway, which is responsible for regulating glucose metabolism and energy homeostasis. The insulin/IGF-1 pathway is a well-established target for many diseases, including diabetes, and SMIM6 has been implicated in this pathway.

SMIM6 is also involved in the regulation of inflammation and cellular stress. It has been shown to play a role in the regulation of inflammation and has been linked to the production of pro-inflammatory cytokines. This suggests that SMIM6 may be a useful target for interventions aimed at reducing inflammation and promoting immune tolerance.

In addition to its role in glucose metabolism and inflammation, SMIM6 is also implicated in a variety of other processes that are important for human health, including cell signaling, DNA replication, and cell division. It has been shown to play a role in regulating cell signaling pathways, including those involved in cell growth, differentiation, and apoptosis.

SMIM6 is also a potential biomarker for a variety of diseases, including cancer. Its expression has been shown to be elevated in a variety of cancer types, including breast, ovarian, and colorectal cancers. This suggests that SMIM6 may be a useful target for cancer therapies that aim to reduce cancer cell proliferation.

In conclusion, SMIM6 is a protein that is expressed in a variety of tissues and cells in the body and is involved in a wide range of physiological processes. Its functions as a glucose sensor, regulator of the insulin/IGF-1 signaling pathway, and regulator of inflammation make it an attractive target for drug development. Furthermore, its role in cell signaling and DNA replication make it a potential biomarker for a variety of diseases, including cancer. Further research is needed to fully understand the role of SMIM6 in these processes and to develop effective therapies that target it.

Protein Name: Small Integral Membrane Protein 6

The "SMIM6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SMIM6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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