Location and Expression of Pseudogene Loc646970 (G646970)
Location and Expression of Pseudogene Loc646970
Loc646970 is a gene located on chromosome 5 open reading frame 15 (ORF15) of the human genome. It is a pseudogene, which means that it is a stretch of DNA that does not code for any functional protein, but can still be transcribed into RNA. Loc646970 is of interest as a potential drug target or biomarker due to its unique genetic makeup and location on the genome.
Location and Expression
Loc646970 is located on the long arm of chromosome 5 at position 138.92馃槈 139.06馃敔. It is a region of DNA that is known as the ORF15 gene. ORF15 is a 15-base RNA molecule that is transcribed from the DNA template in the ORF15 gene. The ORF15 gene is a pseudogene, which means that it is a stretch of DNA that does not code for any functional protein, but can still be transcribed into RNA.
Unique Genetic Feature
Loc646970 is unique in that it is a pseudogene that is located on the ORF15 gene. ORF15 is a well-established gene that encodes a protein known as CRM1 (cysteinyl-prolyl-isoleucine repeat-containing 1). CRM1 is a protein that is involved in a variety of cellular processes, including cell signaling, DNA replication, and stress response.
Location of the pseudogene
The location of Loc646970 on the ORF15 gene is also unique. ORF15 is located on the long arm of chromosome 5, and Loc646970 is located on the same arm but a different position. This means that Loc646970 is not in close proximity to other genes on the ORF15 gene, which could make it more difficult to interact with them and potentially more difficult to target with drugs.
Potential Drug Target
Loc646970's unique genetic features make it a promising candidate for drug targeting. One potential mechanism by which Loc646970 could be targeted is by inhibiting the activity of CRM1, which is the protein encoded by the ORF15 gene. CRM1 is involved in a variety of cellular processes, including cell signaling, DNA replication, and stress response. By inhibiting CRM1 activity, a drug could potentially interfere with the function of the ORF15 gene and potentially lead to cellular changes that are harmful or beneficial.
Another potential mechanism by which Loc646970 could be targeted is by modifying the expression of the ORF15 gene. By either increasing or decreasing the amount of RNA produced from the ORF15 gene, a drug could potentially interfere with the function of the gene and lead to cellular changes that are harmful or beneficial.
Biomarker
Loc646970 could also be used as a biomarker for a variety of diseases. For example, if a drug is able to inhibit the activity of CRM1, it could potentially be used to treat diseases that are characterized by the over-expression of CRM1, such as cancer. Alternatively, if a drug is able to increase the amount of RNA produced from the ORF15 gene, it could potentially be used to treat diseases that are characterized by the under-expression of ORF15, such as genetic disorders.
Conclusion
Loc646970 is a unique pseudogene that is located on chromosome 5 open reading frame 15. Its unique genetic features, including its location on the ORF15 gene, make it a promising candidate for drug targeting and biomarker development. Further research is needed to fully understand the function of Loc646970 and its potential as a drug target or biomarker.
Protein Name: Chromosome 5 Open Reading Frame 15 Pseudogene
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More Common Targets
LOC647115 | LOC647132 | LOC647481 | LOC649133 | LOC650157 | LOC650226 | LOC651536 | LOC652276 | LOC652608 | LOC653303 | LOC653503 | LOC653513 | LOC653631 | LOC653653 | LOC653698 | LOC727751 | LOC728024 | LOC728098 | LOC728114 | LOC728138 | LOC728376 | LOC728392 | LOC728417 | LOC728485 | LOC728554 | LOC728660 | LOC728688 | LOC728715 | LOC728739 | LOC728743 | LOC728877 | LOC728989 | LOC729086 | LOC729164 | LOC729173 | LOC729218 | LOC729296 | LOC729444 | LOC729609 | LOC729683 | LOC729732 | LOC729737 | LOC729815 | LOC729870 | LOC729887 | LOC729966 | LOC729973 | LOC730098 | LOC730100 | LOC730101 | LOC730183 | LOC730234 | LOC730338 | LOC730668 | LOC90246 | LOC91450 | LOC93429 | LOC93463 | LOC93622 | LOH12CR2 | Long intergenic non-protein coding RNA 1336 | Long intergenic non-protein coding RNA 205 | Long intergenic non-protein coding RNA 266-4, pseudogene | Long-chain-fatty-acid--CoA ligase | LONP1 | LONP2 | LONRF1 | LONRF2 | LONRF3 | LORICRIN | LOX | LOXHD1 | LOXL1 | LOXL1-AS1 | LOXL2 | LOXL3 | LOXL4 | LPA | LPAL2 | LPAR1 | LPAR2 | LPAR3 | LPAR4 | LPAR5 | LPAR6 | LPCAT1 | LPCAT2 | LPCAT3 | LPCAT4 | LPGAT1 | LPIN1 | LPIN2 | LPIN3 | LPL | LPO | LPP | LPP-AS1 | LPP-AS2 | LPXN | LRAT
