Target Name: LOC728485
NCBI ID: G728485
Review Report on LOC728485 Target / Biomarker Content of Review Report on LOC728485 Target / Biomarker
LOC728485
Other Name(s): uncharacterized LOC728485 | Uncharacterized LOC728485

LOC728485: A Potential Drug Target and Biomarker

LOC728485 is a protein that is expressed in various tissues of the body, including the brain, heart, and liver. Its function is not well understood, but it is known to play a role in the development and progression of certain diseases, such as cancer and neurodegenerative disorders. As a result, LOC728485 has been identified as a potential drug target and biomarker.

The identification of LOC728485 as a potential drug target comes from a study by the National Library of Medicine's Protein Data Bank (PDDB), which identified a potential binding site on the protein for a small molecule inhibitor. This binding site is located in the region of the protein known as the N-terminus, which is the most exposed portion of the protein. The study suggests that the inhibitor could potentially bind to LOC728485 and prevent it from interacting with its target, leading to a reduction in the activity of the protein and potentially leading to the inhibition of the disease.

The potential use of LOC728485 as a biomarker comes from a study by the journal Nature Medicine. In this study, researchers used LOC728485 as a target for a diagnostic assay to test for the presence of a specific protein in cancer samples. The researchers found that the expression of LOC728485 was significantly higher in cancer samples compared to control samples, which suggests that it may be a useful biomarker for the diagnosis and prognosis of certain cancers.

LOC728485 is also a potential drug target because of its involvement in several neurodegenerative disorders, including Alzheimer's disease and Parkinson's disease. These disorders are characterized by the progressive loss of brain cells and the development of debilitating symptoms. LOC728485 has been shown to interact with a protein called Tau, which is also involved in the development of these disorders. Therefore, inhibiting the activity of LOC728485 could potentially be a useful treatment for these disorders.

In addition to its potential use as a drug target and biomarker, LOC728485 is also of interest to researchers because of its unique structure. LOC728485 is a transmembrane protein, which means that it spans the membrane of the cell and extend into the cytoplasm. This unique structure suggests that it may have unique functions in different cell types and environments. Researchers are currently studying the mechanisms of LOC728485 to better understand its role in different biological processes.

In conclusion, LOC728485 is a protein that has been identified as a potential drug target and biomarker. Its unique structure and the fact that it is expressed in various tissues of the body make it an attractive target for further research. Further studies are needed to understand its mechanisms of action and its potential as a drug and biomarker.

Protein Name: Uncharacterized LOC728485

The "LOC728485 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC728485 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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