Target Name: FBXL14
NCBI ID: G144699
Review Report on FBXL14 Target / Biomarker Content of Review Report on FBXL14 Target / Biomarker
FBXL14
Other Name(s): FXL14_HUMAN | Fbl14 | F-box and leucine-rich repeat protein 14 | MGC40195 | F-box/LRR-repeat protein 14 | F-box and leucine rich repeat protein 14 | OTTHUMP00000115427

Unlocking The Potential of FBXL14: A Protein Involved in A Variety of Physiological Processes

FBXL14, also known as FXL14 or HUMAN, is a protein that is expressed in various tissues of the human body, including the brain, heart, liver, and kidneys. It is a member of the FXL family of proteins, which are known for their role in the regulation of endothelial cells, including the process of cell signaling and angiogenesis.

One of the unique features of FBXL14 is its ability to interact with several different proteins, including the transcription factor NF-kappa-B. This interaction between FXL14 and NF-kappa-B has been shown to play a role in a variety of physiological processes, including the regulation of inflammation, inflammation-related pain, and the development of certain diseases.

In addition to its role in cell signaling, FXL14 has also been shown to be involved in the regulation of cellular processes that are important for tissue repair and regeneration. This may be of particular interest in the context of diseases that involve cellular dysfunction, such as cancer, where cells are often resistant to drugs and have a poor ability to repair themselves.

FXL14 has also been shown to be involved in the regulation of cell adhesion, which is the process by which cells stick together to form tissues and organs. This may be of particular interest in diseases that involve cell dysfunction, such as heart failure, where cells may not be able to stick together effectively to form a supportive matrix.

In addition to its role in cell signaling and adhesion, FXL14 has also been shown to be involved in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. This may be of particular interest in diseases that involve the breakdown of tissues or organs, such as regenerative diseases or diseases that cause tissue death.

Overall, FBXL14 is a protein that has been shown to be involved in a variety of physiological processes that are important for the health and well-being of the human body. As such, it may be a promising drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of FXL14 in cell signaling and to identify potential therapeutic approaches for its use.

Protein Name: F-box And Leucine Rich Repeat Protein 14

Functions: Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1

The "FBXL14 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FBXL14 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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