NBF15: A Potential Drug Target for Neuroblastomas (G284565)
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NBF15: A Potential Drug Target for Neuroblastomas
Neuroblastoma Breakpoint Family Member 15 (NBF15) is a protein that is expressed in a variety of tissues, including brain, pancreas, and muscle. It is a member of the neuroblastoma breakpoint family, which is a group of proteins that are involved in the regulation of cell division and growth. NBF15 has been shown to play a role in the development and progression of neuroblastomas, which are a type of cancer that develops from neural stem cells.
Recent studies have suggested that NBF15 may be a drug target or biomarker for the treatment of neuroblastomas. One reason for this is that NBF15 has been shown to be involved in the development of neuroblastoma cell lines in culture. Researchers have used techniques such as RNA interference and immunoprecipitation to show that NBF15 is involved in the regulation of cell growth and survival.
Another potential mechanism by which NBF15 may be involved in the treatment of neuroblastomas is its role in cell-cell fusion. Neuroblastomas are known for their ability to undergo rapid cell-cell fusion, which allows them to develop into highly aggressive and treatment-resistant tumors. Researchers have shown that NBF15 is involved in the regulation of cell-cell fusion in neuroblastomas, and that inhibiting this process may be a promising strategy for the treatment of neuroblastomas.
In addition to its potential role in the treatment of neuroblastomas, NBF15 has also been shown to be a potential biomarker for the disease. The expression of NBF15 has been shown to be associated with the development and progression of neuroblastomas, and researchers have used techniques such as gene expression profiling to identify potential biomarkers for the disease.
While more research is needed to fully understand the role of NBF15 in the treatment of neuroblastomas, it is clear that NBF15 is an important protein that is involved in the regulation of cell growth and survival. Further studies are needed to determine the full extent of NBF15's involvement in the development and treatment of neuroblastomas.
Protein Name: NBPF Member 15
The "NBPF15 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NBPF15 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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