Hikeshhi: A Protein Target for Drug Development (G51501)

Target Name: HIKESHI

NCBI ID: G51501

HIKESHI

Hikeshhi: A Protein Target for Drug Development

Hikeshhi, also known as Hikeshhi variant 1, is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the defining features of Hikeshhi is its unique structure. It is a transmembrane protein that consists of an extracellular region, a transmembrane region, and an intracellular region. The extracellular region is involved in cell adhesion and signaling, the transmembrane region is responsible for the protein's localization and interactions with other molecules, and the intracellular region contains the protein's catalytic and regulatory activities.

Hikeshhi's unique structure and its involvement in multiple cellular processes make it an attractive target for drug development. One of the main advantages of targeting Hikeshhi is that it is highly druggable, as many of its functions are localized to the cytosol, which is the fluid inside the cell. Additionally, Hikeshhi is a protein that is expressed in a wide range of tissues, which makes it easier to find potential drugs that work against it in these tissues.

Hikeshhi has been implicated in a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have suggested that Hikeshhi may be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, Hikeshhi has been shown to be involved in the development of cancer, and may be a useful biomarker for this disease.

In addition to its potential role in disease, Hikeshhi has also been shown to be involved in many important cellular processes. For example, it is involved in cell signaling, cell adhesion, and the regulation of cell growth. Additionally, Hikeshhi is involved in the formation of the cytoskeleton, which is the structure that gives cells shape and stability.

Given its unique structure and its involvement in multiple cellular processes, Hikeshhi is an attractive target for drug development. Many small molecules and other drugs have been shown to be able to interact with Hikeshhi, and studies have suggested that these drugs may be able to inhibit its functions or modulate its activity in a variety of ways.

In conclusion, Hikeshhi is a protein that is expressed in various tissues of the body and is involved in a number of cellular processes. Its unique structure and its involvement in multiple diseases make it an attractive target for drug development. While more research is needed to fully understand the functions of Hikeshhi and its potential as a drug target, its potential as a biomarker for disease and its involvement in cellular processes make it a promising area for further study.

Protein Name: Heat Shock Protein Nuclear Import Factor Hikeshi

Functions: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus

The "HIKESHI Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HIKESHI comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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