Target Name: ATP7B
NCBI ID: G540
Review Report on ATP7B Target / Biomarker Content of Review Report on ATP7B Target / Biomarker
ATP7B
Other Name(s): ATP7B variant 2 | Copper-transporting ATPase 2 (isoform b) | WC1 | PWD | ATPase, Cu(2+)- transporting, beta polypeptide | WD | ATPase copper transporting beta variant 2 | copper-transporting protein ATP7B | ATPase, Cu++ transporting, beta polypeptide | copper pump 2 | ATP7B_HUMAN | Copper-transporting ATPase 2 | ATP7B variant 1 | WND/140 kDa | ATPase copper transporting beta | Copper pump 2 | Copper-transporting ATPase 2 (isoform a) | WND | ATPase copper transporting beta, transcript variant 1 | Wilson disease-associated protein

ATP7B: A Potential Drug Target and Biomarker

ATP (adenylyl cyclic polymerase) is a highly conserved enzyme that is involved in the production of adenosine, a molecule that plays a crucial role in various cellular processes. In recent years, researchers have discovered that ATP7B, a protein that is expressed in various tissues and cells, has unique properties that make it an attractive drug target and biomarker.

The ATP7B protein is characterized by its ability to catalyze the transfer of a phosphate group from a phosphate-containing substrate to an ADP molecule. This reaction is a key step in the production of adenosine, and as a result, ATP7B has been shown to play a critical role in the regulation of cellular processes such as inflammation, stress response, and metabolism.

One of the key features of ATP7B is its ability to interact with multiple signaling pathways. For example, ATP7B has been shown to be involved in the regulation of pain perception, inflammation, and cell survival. Additionally, ATP7B has been shown to play a role in the regulation of cellular metabolism, including the regulation of DNA replication and cell growth.

Given its involvement in multiple cellular processes, ATP7B has become a focus of interest for researchers as a potential drug target. By modulating the activity of ATP7B, researchers can study its role in various cellular processes and develop new treatments for a variety of diseases.

One approach to modulating the activity of ATP7B is through the use of small molecules, such as drugs that bind to ATP7B's active site. These small molecules can modulate the activity of ATP7B by altering its catalytic activity, stability, or interactions with other cellular components.

In addition to its potential as a drug target, ATP7B has also been identified as a potential biomarker for a variety of diseases. For example, researchers have shown that decreased levels of ATP7B have been associated with various diseases, including heart disease, cancer, and neurodegenerative diseases. Additionally, increased levels of ATP7B have been observed in diseases such as Alzheimer's and Parkinson's, further supporting its potential as a biomarker.

In conclusion, ATP7B is a protein that has unique properties that make it an attractive drug target and biomarker. Its ability to interact with multiple signaling pathways and its involvement in various cellular processes make it an attractive target for researchers. Additionally, its potential as a drug and biomarker make it a promising area for future research.

Protein Name: ATPase Copper Transporting Beta

Functions: Copper ion transmembrane transporter involved in the export of copper out of the cells. It is involved in copper homeostasis in the liver, where it ensures the efflux of copper from hepatocytes into the bile in response to copper overload

The "ATP7B Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ATP7B comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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