SMIM11: A Drug Target / Disease Biomarker (G54065)

Target Name: SMIM11

NCBI ID: G54065

SMIM11

SMIM11: A Drug Target / Disease Biomarker

SMIM11 is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a member of the superfamily of evolutionarily conserved structurally similar proteins (SCSPs), which includes other well-known proteins such as SMIM1, SMIM2, and SMIM3. These proteins are involved in a variety of cellular processes, including cell signaling, metabolism, and inflammation.

SMIM11 is of particular interest as a potential drug target, due to its involvement in several key cellular processes that are often disrupted in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It is also a good candidate as a biomarker, as its expression has been shown to be affected by a variety of factors, including genetic, hormonal, and environmental factors.

One of the key functions of SMIM11 is its role in the intracellular signaling pathway known as the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is often disrupted in various diseases. SMIM11 is a key regulator of TGF-β signaling, and has been shown to play a role in the regulation of cell proliferation, differentiation, and survival.

In addition to its role in TGF-β signaling, SMIM11 is also involved in the regulation of cellular metabolism and energy homeostasis. It is a regulator of the protein kinase B (PKB), which is involved in the regulation of cell signaling and metabolism. It is also a regulator of the energy-producing enzyme succinyl-CoA synthase (SCS), which is involved in the metabolism of fatty acids and amino acids.

SMIM11 is also involved in the regulation of inflammation and immune responses. It is a regulator of the chemokine receptor CXCR1, which is involved in the regulation of immune cell function. It is also a regulator of the cytokine TLR4, which is involved in the regulation of inflammation and immune responses.

SMIM11 is a versatile protein that is involved in a variety of cellular processes that are important for human health and disease. Its involvement in TGF-β signaling, cellular metabolism, energy homeostasis, and inflammation make it an attractive target for drug development and research. Further studies are needed to fully understand the role of SMIM11 in these processes and to develop effective therapies based on its properties.

Protein Name: Small Integral Membrane Protein 11

The "SMIM11 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SMIM11 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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