Target Name: NXPE4
NCBI ID: G54827
Review Report on NXPE4 Target / Biomarker Content of Review Report on NXPE4 Target / Biomarker
NXPE4
Other Name(s): Neurexophilin and PC-esterase domain family member 4, transcript variant 1 | C11orf33 | Protein FAM55D | FAM55D | NXPE family member 4 (isoform 1) | protein FAM55D | Neurexophilin and PC-esterase domain family member 4, transcript variant 2 | FLJ20127 | NXPE family member 4 (isoform 2) | NXPE4 variant 2 | family with sequence similarity 55, member D | neurexophilin and PC-esterase domain family member 4 | NXPE4 variant 1 | NXPE4_HUMAN | NXPE family member 4 | Family with sequence similarity 55, member D

NXPE4: A Potential Drug Target and Biomarker

NXPE4 is a novel protein that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. NXPE4 is a cytoplasmic protein that is expressed in most tissues and cells, including brain, heart, liver, and muscle. It is composed of two distinct chains, A and B, that are held together by a disulfide bond. NXPE4 has been shown to play a role in various cellular processes, including cell signaling, cell adhesion, and stress response.

Drug Target Potential

NXPE4 has been identified as a potential drug target due to its unique structure and its involvement in various cellular processes. One of the key reasons for its potential as a drug target is its cytoplasmic expression, which suggests that it is not expressed in the plasma or other body fluids. This makes it more difficult for the drug to interact with it and increase its concentration in the body. However, its expression in the cytoplasm suggests that it may be more accessible to small molecules that can interact with it. Additionally, NXPE4 has been shown to play a role in various cellular signaling pathways, including the PI3K/Akt signaling pathway. This suggests that it may be a good target for drugs that target this pathway.

Biomarker Potential

NXPE4 has also been identified as a potential biomarker for various diseases. Its unique structure and its involvement in various cellular processes make it an attractive candidate for use as a biomarker. For example, NXPE4 has been shown to be expressed in various tissues and cells, including brain, heart, and liver. This suggests that it may be a good biomarker for diseases that affect these organs. Additionally, NXPE4 has been shown to play a role in various cellular signaling pathways, including the PI3K/Akt signaling pathway. This suggests that it may be a good biomarker for diseases that are characterized by inflammation or cellular signaling dysfunction.

Expression and Measurement

To further evaluate the potential of NXPE4 as a drug target and biomarker, researchers have used various techniques to measure its expression and activity in various tissues and cells. For example, researchers have used Western blotting to measure the expression of NXPE4 in different tissues, including brain, heart, and liver. They have also used biochemical assays, such as protein kinase assays, to measure the activity of NXPE4 in different cellular signaling pathways.

Conclusion

In conclusion, NXPE4 is a novel protein that has been identified as a potential drug target and biomarker for various diseases. Its unique structure and its involvement in various cellular processes make it an attractive candidate for use as a drug target or biomarker. Further research is needed to fully evaluate its potential and determine its utility as a drug or biomarker.

Protein Name: Neurexophilin And PC-esterase Domain Family Member 4

The "NXPE4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NXPE4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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