NXPH2: A Protein of Unclear Function as A Drug Target Or Biomarker

Target Name: NXPH2

NCBI ID: G11249

NXPH2

Other Name(s): MGC125478 | NPH2 | Neurexophilin-2 | MGC125479 | Neurexophilin 2 | neurexophilin 2 | MGC125477 | MGC125480 | NXPH2_HUMAN

NXPH2: A Protein of Unclear Function as A Drug Target Or Biomarker

NXPH2, also known as MGC125478, is a protein that is expressed in various tissues and cells of the human body. Its function is not well understood, but it is known to play a role in the development and progression of many diseases, including cancer. As a drug target or biomarker, NXPH2 is of great interest to researchers because it can be targeted with small molecules or other therapeutic agents to treat diseases.

NXPH2 is a member of the heat shock protein (HSP) family, which are proteins that are expressed in high levels in response to changes in temperature or other stressors. HSPs have been implicated in many diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. NXPH2 is specifically known for its role in the development of cancer, and it is thought to promote the growth and survival of cancer cells.

One of the key functions of NXPH2 is its role in cell signaling. NXPH2 has been shown to play a role in several signaling pathways that are involved in cancer development, including the TGF-β pathway and the PI3K/Akt pathway. These pathways are involved in cell growth, apoptosis (programmed cell death), and angiogenesis (the formation of new blood vessels), and are often disrupted in cancer. By promoting the growth and survival of cancer cells, NXPH2 may contribute to the development and progression of cancer.

Another function of NXPH2 is its role in cell migration. NXPH2 has been shown to play a role in the migration of cancer cells, both in the primary and metastatic phases of cancer. This may contribute to the development of cancer stem cells, which are cancer cells that have the ability to maintain a self-sustaining and immortal state. By promoting the migration of cancer cells, NXPH2 may also contribute to the development of cancer stem cells.

In addition to its role in cell signaling and cell migration, NXPH2 is also thought to play a role in the regulation of cellular processes that are important for cancer development. For example, NXPH2 has been shown to play a role in the regulation of the apoptosis pathway, which is the process by which cells undergo programmed cell death. This may contribute to NXPH2's potential as a drug target for cancer treatment.

As a drug target or biomarker, NXPH2 is of great interest to researchers because it can be targeted with small molecules or other therapeutic agents. For example, researchers have shown that NXPH2 can be inhibited by small molecules such as rapamycin, a drug that is commonly used to treat cancer. In addition, researchers have also shown that NXPH2 can be targeted by antibodies that are designed to recognize and bind to specific regions of the protein.

In conclusion, NXPH2 is a protein that is expressed in various tissues and cells of the human body. Its function is not well understood, but it is known to play a role in the development and progression of many diseases, including cancer. As a drug target or biomarker, NXPH2 is of great interest to researchers because it can be targeted with small molecules or other therapeutic agents to treat diseases. Further research is needed to fully understand the role of NXPH2 in cell signaling and other cellular processes, as well as its potential as a drug target or biomarker for cancer.

Protein Name: Neurexophilin 2

Functions: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors

The "NXPH2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about NXPH2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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