Target Name: FNBP1L
NCBI ID: G54874
Review Report on FNBP1L Target / Biomarker Content of Review Report on FNBP1L Target / Biomarker
FNBP1L
Other Name(s): Formin-binding protein 1-like (isoform 3) | Formin binding protein 1 like, transcript variant 1 | Formin-binding protein 1-like | FNBP1L variant 3 | Transducer of Cdc42-dependent actin assembly protein 1 | formin binding protein 1 like | transducer of Cdc42-dependent actin assembly protein 1 | transducer of Cdc42-dependent actin assembly 1 | Formin-binding protein 1-like (isoform 1) | Transducer of Cdc42-dependent actin assembly 1 | FNBP1L variant 1 | FBP1L_HUMAN | toca-1 | C1orf39 | Toca-1 | TOCA1 | Formin binding protein 1 like, transcript variant 3

Unlocking the Potential of FNBP1L as a Drug Target and Biomarker

FBNBP1L, a 21-kDa protein, has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. FBNBP1L plays a critical role in the regulation of cell growth, differentiation, and survival, and its dysfunction has been implicated in numerous diseases. This article aims to provide an overview of FBNBP1L, its functions, potential drug targets, and its potential as a biomarker.

FBNBP1L: A Protein Lending a Hand to Cellular Processes

FBNBP1L is a member of the FBNBP gene family, which encodes a protein involved in the regulation of cell adhesion and migration. The FBNBP1L gene has four exons, and its protein has a molecular weight of 21 kDa. FBNBP1L is highly conserved, with a calculated pI of 4.97. FBNBP1L is predominantly expressed in the brain, heart, and pancreas, and its expression is also observed in other tissues, including muscle and kidney.

FBNBP1L's Functions in Cellular Processes

FBNBP1L is involved in several cellular processes that are crucial for cell growth, differentiation, and survival. One of its most significant functions is the regulation of cell adhesion and migration. FBNBP1L is known to interact with several adhesion molecules, including cadherins, E-cadherins, and N-cadherins. These interactions regulate the movement of cells during various signaling pathways, including cell migration, invasion, and angiogenesis.

FBNBP1L is also involved in the regulation of cell survival and proliferation. It has been shown to play a role in the cell cycle, with a G1-S transition and a G2-M transition being observed in its expression profiles. Additionally, FBNBP1L has been shown to promote cell proliferation and contribute to the survival of cancer cells.

Potential Drug Targets

FBNBP1L has been identified as a potential drug target due to its involvement in several diseases. Its dysfunction in cell adhesion and migration has been implicated in various neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Additionally, FBNBP1L has been shown to be involved in the regulation of cancer cell growth and survival, making it an attractive target for cancer therapies.

FBNBP1L has also been identified as a potential biomarker for various diseases, including cancer. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and colorectal cancers. Additionally, FBNBP1L has been shown to be involved in the regulation of inflammation, which is a crucial factor in the development of many diseases, including cancer.

Potential as a Biomarker

FBNBP1L has also been identified as a potential biomarker for various diseases. Its expression has been shown to be elevated in various types of cancer, including breast, ovarian, and colorectal cancers. Additionally, FBNBP1L has been shown to be involved in the regulation of inflammation, which is a crucial factor in the development of many diseases, including cancer. These findings suggest that FBNBP1L may be a useful biomarker for the diagnosis and monitoring of various diseases, including cancer.

Conclusion

In conclusion, FBNBP1L is a protein that plays a critical role in several cellular processes that are crucial for

Protein Name: Formin Binding Protein 1 Like

Functions: Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens

The "FNBP1L Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FNBP1L comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

FNBP1P1 | FNBP4 | FNDC1 | FNDC10 | FNDC11 | FNDC3A | FNDC3B | FNDC4 | FNDC5 | FNDC7 | FNDC8 | FNDC9 | FNIP1 | FNIP2 | FNTA | FNTB | FOCAD | Focal Adhesion Kinases (FAK) | Folate Receptor | FOLH1 | FOLH1B | Follicle stimulating hormone | FOLR1 | FOLR2 | FOLR3 | Formin homology 2 domain-containing proteins | FOS | FOSB | FOSL1 | FOSL2 | FOSL2-AS1 | FOXA1 | FOXA2 | FOXA3 | FOXB1 | FOXB2 | FOXC1 | FOXC2 | FOXC2-AS1 | FOXCUT | FOXD1 | FOXD2 | FOXD2-AS1 | FOXD3 | FOXD3-AS1 | FOXD4 | FOXD4L1 | FOXD4L3 | FOXD4L4 | FOXD4L5 | FOXD4L6 | FOXE1 | FOXE3 | FOXF1 | FOXF2 | FOXF2-DT | FOXG1 | FOXG1-AS1 | FOXH1 | FOXI1 | FOXI2 | FOXI3 | FOXJ1 | FOXJ2 | FOXJ3 | FOXK1 | FOXK2 | FOXL1 | FOXL2 | FOXL2NB | FOXL3-OT1 | FOXM1 | FOXN1 | FOXN2 | FOXN3 | FOXN3-AS1 | FOXN3-AS2 | FOXN4 | FOXO1 | FOXO1B | FOXO3 | FOXO3B | FOXO4 | FOXO6 | FOXO6-AS1 | FOXP1 | FOXP2 | FOXP3 | FOXP4 | FOXP4-AS1 | FOXQ1 | FOXR1 | FOXR2 | FOXRED1 | FOXRED2 | FOXS1 | FP588 | FPGS | FPGT | FPGT-TNNI3K