FNDC1: A Protein Involved in Cell-Cell Adhesion and Multiple Signaling Pathways

Target Name: FNDC1

NCBI ID: G84624

FNDC1

FNDC1: A Protein Involved in Cell-Cell Adhesion and Multiple Signaling Pathways

Fibronectin type III domain containing 1 (FNDC1) is a protein that is expressed in various tissues throughout the body. It is a member of the FNDC family, which is a family of proteins that are involved in cell-cell adhesion. FNDC1 is one of the proteins that belong to the type III subfamily of FNDCs.

The FNDC family plays a crucial role in cell-cell adhesion, as it helps to regulate the interactions between cells. FNDCs are involved in many different processes in the body, including the development and maintenance of tissues and organs, as well as the regulation of inflammation.

FNDC1 is a 21-kDa protein that is expressed in various tissues throughout the body. It is highly conserved, with a calculated pI of 6.5. FNDC1 is primarily expressed in the liver, as well as being found in other tissues such as the heart, kidneys, and pancreas.

FNDC1 has several unique features that make it an interesting drug target. One of its most notable characteristics is its ability to interact with various signaling pathways. FNDC1 has been shown to interact with several different signaling pathways, including the TGF-β pathway and the Wnt pathway.

The TGF-β pathway is a well-established signaling pathway that is involved in the regulation of cell growth, differentiation, and inflammation. FNDC1 has been shown to play a role in the regulation of TGF-β signaling in various tissues. For example, studies have shown that FNDC1 can inhibit the activity of the TGF-β receptor, which is involved in the regulation of cell growth and differentiation.

The Wnt pathway is another signaling pathway that is involved in the regulation of cell growth and development. FNDC1 has also been shown to interact with the Wnt pathway, and this interaction may be involved in the regulation of cell proliferation and differentiation.

In addition to its ability to interact with multiple signaling pathways, FNDC1 is also known for its role in the regulation of cell adhesion. FNDC1 is involved in the formation of tight junctions, which are a type of cell-cell adhesion structure that helps to maintain the integrity of tissues.

FNDC1 is also involved in the regulation of cell signaling pathways that are important for the development and maintenance of tissues and organs. For example, studies have shown that FNDC1 can regulate the activity of the Notch pathway, which is involved in the regulation of stem cell proliferation and differentiation.

Given its ability to interact with multiple signaling pathways and its role in the regulation of cell adhesion, FNDC1 is an attractive drug target. There is ongoing research into the use of small molecules and other compounds to target FNDC1, with the goal of developing new treatments for various diseases.

In conclusion, FNDC1 is a protein that is expressed in various tissues throughout the body and is involved in the regulation of cell-cell adhesion and several signaling pathways. Its unique properties make it an attractive drug target, with potential for the development of new treatments for various diseases. Further research is needed to fully understand the role of FNDC1 in the regulation of cell biology and to develop effective treatments.

Protein Name: Fibronectin Type III Domain Containing 1

Functions: May be an activator of G protein signaling

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