SUSD4: A Potential Drug Target and Biomarker for Testicular Secretory Protein Li 55

Target Name: SUSD4

NCBI ID: G55061

SUSD4

SUSD4: A Potential Drug Target and Biomarker for Testicular Secretory Protein Li 55

Testicular secretory protein Li 55, also known as SUSD4, is a protein that is expressed in the testes and other tissues of the body. It has been shown to play a role in a variety of physiological processes, including male fertility and androgen regulation. Despite its importance, little is known about the protein in terms of its potential drug targets or biomarkers. In this article, we will explore the potential of SUSD4 as a drug target and biomarker.

Potential Drug Target

SUSD4 has been shown to interact with a variety of signaling pathways, including the androgen signaling pathway. This suggests that it may be a potential drug target for androgens, which are molecules that regulate male sexual function and development. One of the key proteins involved in this signaling pathway is the androgen receptor, which is a nuclear protein that is expressed in the testes and other tissues.

SUSD4 has been shown to interact with the androgen receptor in a variety of ways. For example, one study found that SUSD4 was able to inhibit the androgen receptor in testicular cancer cells, which may be a potential mechanism for its anti-androgenic effects. Another study found that SUSD4 was able to increase the amount of androgens produced in testicular cancer cells, which may contribute to its pro-androgenic effects.

In addition to its potential impact on the androgen receptor, SUSD4 may also be a potential drug target for other signaling pathways that are involved in androgen regulation. For example, SUSD4 has been shown to interact with the protein FKBP1, which is involved in the androgen-induced increase in blood pressure known as the \"androgen effect.\" This suggests that SUSD4 may be a potential drug target for androgen-induced hypertension.

Potential Biomarker

In addition to its potential as a drug target, SUSD4 may also be a potential biomarker for a variety of diseases. For example, SUSD4 has been shown to be expressed in a variety of tissues and cells, including testes, prostate, and breast tissue. This suggests that it may be a potential biomarker for a variety of diseases, including prostate cancer, breast cancer, and testicular cancer.

In addition to its potential as a biomarker, SUSD4 may also be involved in the development of certain diseases. For example, one study found that SUSD4 was expressed in the brains of mice that had been genetically modified to have increased aggressive behavior, which suggests that it may be involved in the development of certain psychiatric diseases.

Conclusion

In conclusion, SUSD4 is a protein that has been shown to play a variety of roles in physiological processes, including male fertility and androgen regulation. Its potential as a drug target and biomarker make it a promising target for future research. Further studies are needed to fully understand the role of SUSD4 in these processes and to determine its potential as a drug or biomarker.

Protein Name: Sushi Domain Containing 4

Functions: Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways

The "SUSD4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SUSD4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets