EXOC1: A Protein Involved in Exocyst Structure and Protein Transport

Target Name: EXOC1

NCBI ID: G55763

EXOC1

EXOC1: A Protein Involved in Exocyst Structure and Protein Transport

EXOCYST Complex Component 1 (EXOC1) is a protein that plays a critical role in the exocyst structure of eukaryotic cells. It is a key component of the exocyst complex, which is responsible for the formation and disassembly of vesicles that transport proteins from the cytoplasm to the plasma membrane. EXOC1 is essential for the proper functioning of the exocyst complex, and its levels have been implicated in a variety of cellular processes, including protein transport, cell signaling, and neurodegeneration. As a result, EXOC1 has emerged as a promising drug target and a potential biomarker for a variety of diseases.

EXOC1 is a 21-kDa protein that is composed of two main subunits, EXOC1A and EXOC1B. EXOC1A is the N-terminus of the protein and EXOC1B is the C-terminus. The two subunits are held together by a disulfide bond, and the entire protein has a calculated pI of approximately 6.5.

EXOC1 is involved in the formation and disassembly of exocysts, which are specialized vesicles that transport proteins from the cytoplasm to the plasma membrane. During the exocyst formation process, EXOC1A is translocation to the cytoplasmic side of the membrane and EXOC1B is translocation to the plasma membrane side. When the exocyst is disassembled, EXOC1B is translocation back to the cytoplasm, while EXOC1A remains on the plasma membrane side.

In addition to its role in exocyst formation and disassembly, EXOC1 is also involved in the regulation of protein transport and cell signaling. It has been shown to play a role in the regulation of the trafficking of various proteins, including the protein known as T-cell factor (T-CF), a critical regulator of T-cell development and function.

EXOC1 has also been shown to be involved in the regulation of cell signaling pathways that are important for cellular processes such as cell growth, apoptosis, and neurodegeneration. For example, EXOC1 has been shown to play a role in the regulation of the neurotransmitter tyrosine, which is involved in the regulation of various cellular processes, including neurotransmission, neuroendocrine function, and stress response.

In conclusion, EXOC1 is a protein that is involved in a variety of cellular processes that are important for the proper functioning of cells. Its role in the regulation of exocyst formation and disassembly, as well as its involvement in the regulation of protein transport and cell signaling pathways, make it a promising drug target and a potential biomarker for a variety of diseases. Further research is needed to fully understand the complex functions of EXOC1 in eukaryotic cells, and to determine its potential as a drug or biomarker.

Protein Name: Exocyst Complex Component 1

Functions: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

The "EXOC1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EXOC1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets