Target Name: EVC2
NCBI ID: G132884
Review Report on EVC2 Target / Biomarker Content of Review Report on EVC2 Target / Biomarker
EVC2
Other Name(s): EVC2 variant 1 | EvC ciliary complex subunit 2, transcript variant 1 | Limbin (isoform 2) | EVC2 variant X1 | Limbin | Ellis-van Creveld syndrome protein 2 | EVC2 variant 2 | LBN_HUMAN | EvC ciliary complex subunit 2, transcript variant X1 | Ellis van Creveld syndrome 2 | LBN | Limbin (isoform 1) | ellis-van Creveld syndrome protein 2 | Limbin isoform 2 | WAD | Limbin (isoform X1) | LIMBIN | EvC ciliary complex subunit 2, transcript variant 2 | EvC ciliary complex subunit 2

EVC2: A Potential Drug Target Or Biomarker

EVC2 (EVC2) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a key regulator of cell growth and differentiation, and is involved in the development and maintenance of tissues. In recent Over the years, EVC2 has gained interest as a potential drug target or biomarker due to its unique biology and its involvement in several diseases, including cancer.

EVC2 in Cancer

One of the main ways that EVC2 is associated with cancer is its role in the regulation of cell growth and proliferation. EVC2 has been shown to play a negative role in the development and progression of several types of cancer, including breast, ovarian, and prostate cancer.

For example, studies have shown that EVC2 levels are higher in breast cancer cells compared to normal cells, and that inhibiting EVC2 can lead to the growth arrest and regression of these cells. Similarly, EVC2 has been shown to promote the growth and survival of cancer cells, which may contribute to its role in the development and progression of cancer.

Another way that EVC2 is associated with cancer is its role in cell-cell signaling. EVC2 has been shown to play a role in several cell-cell signaling pathways, including the TGF-β pathway. This pathway is involved in cell growth, differentiation, and survival, and is a key factor in cancer development.

For example, studies have shown that EVC2 can physically interact with the TGF-β receptor, which is a key regulator of TGF-β signaling. This interaction may contribute to the regulation of TGF-β signaling by EVC2, and may be a potential target for cancer treatments.

EVC2 in Inflammation

In addition to its role in cancer development, EVC2 is also involved in the regulation of inflammation. EVC2 has been shown to play a role in the regulation of immune and inflammatory responses, and has been implicated in the development of several inflammatory diseases, including rheumatoid arthritis and multiple sclerosis.

For example, studies have shown that EVC2 levels are higher in individuals with rheumatoid arthritis compared to those without the disease, and that inhibiting EVC2 may be a potential treatment for this disease. Similarly, EVC2 has been shown to contribute to the development and progression of multiple sclerosis, a disease characterized by inflammation and autoimmune damage to the central nervous system.

EVC2 as a Potential Drug Target

The potential utility of EVC2 as a drug target or biomarker makes it an attractive target for researchers to investigate. There are several potential strategies that could be used to target EVC2, including inhibition of its expression, manipulation of its function, and use of small molecules or antibodies to interact with it.

One potential approach to targeting EVC2 is the use of small molecules. Small molecules can be used to inhibit the expression or function of EVC2, and can be administered to cells or used in vitro experiments. For example, researchers have developed small molecules that can inhibit the expression of EVC2, and have shown that these molecules can be effective in reducing the growth and survival of cancer cells.

Another potential approach to targeting EVC2 is the use of antibodies. Antibodies are proteins that are produced by the immune system to recognize and neutralize foreign substances, such as viruses or cancer cells. Researchers have developed antibodies that can specifically recognize and bind to EVC2, and have shown that these antibodies can be effective in reducing the growth and survival of cancer cells.

Conclusion

In conclusion, EVC2 is a protein that is involved in the regulation of cell growth and differentiation, and has been implicated in the development and progression of several types of cancer. As a potential drug target or biomarker, EVC2 is an attractive target for researchers to investigate, and a variety of strategies, including inhibition of its expression, manipulation of its function,

Protein Name: EvC Ciliary Complex Subunit 2

Functions: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis

The "EVC2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EVC2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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