Evplakin, A Protein Regulating Protein Synthesis and Degradation

Target Name: EVPL

NCBI ID: G2125

EVPL

Evplakin, A Protein Regulating Protein Synthesis and Degradation

Evplakin (Envoplakin, transcript variant 1) is a protein that is expressed in the endoplasmic reticulum (ER) and has been shown to play a role in the regulation of various cellular processes. One of the most interesting aspects of Evplakin is its potential as a drug target or biomarker. In this article, we will explore the biology of Evplakin, its potential drug target status, and its potential as a biomarker for various diseases.

Biology of Evplakin

Evplakin is a member of the protein family known as the tyrosine-protein kinase (TPK) family. This family of proteins plays a critical role in the regulation of various cellular processes, including cell growth, differentiation, and survival. Evplakin is a 12-kDa protein that is expressed in the ER and has been shown to play a role in the regulation of protein synthesis and degradation.

One of the most interesting aspects of Evplakin is its potential as a drug target. The TPK family of proteins have been shown to be involved in the regulation of various cellular processes, including cell signaling pathways. Therefore, Evplakin is a potential drug target that could be targeted by small molecules or antibodies to inhibit its activity.

Potential Drug Target

small molecules:

Evplakin is a protein that is involved in the regulation of protein synthesis and degradation. Therefore, small molecules that can inhibit its activity could be useful as drugs. One of the most interesting potential drug targets for Evplakin is the protein tyrosine phosphatase (PTP). PTP is a enzyme that is involved in the regulation of protein tyrosination, which is a critical step in the regulation of various cellular processes. Therefore, inhibiting the activity of PTP could be a potential way to target Evplakin.

Another potential drug target for Evplakin is the protein-protein interaction (PPI) network. PPI networks are complex networks of proteins that interact with each other to regulate various cellular processes. Evplakin is a member of the PPIN network, and therefore, inhibiting its activity could be a potential way to target this network.

Biomarker Potential

Evplakin has the potential to serve as a biomarker for various diseases. One of the most interesting potential biomarkers for Evplakin is its role in the regulation of cellular processes that are affected by disease. For example, Evplakin has been shown to play a role in the regulation of cell death, which is a critical aspect of many diseases, including cancer. Therefore, measuring the expression of Evplakin could be a potential way to diagnose or predict the outcome of diseases that are affected by cell death.

Another potential biomarker for Evplakin is its role in the regulation of protein synthesis and degradation. Many diseases are caused by the regulation of protein synthesis and degradation, and therefore, measuring the expression of Evplakin could be a potential way to diagnose or predict the outcome of diseases that are affected by these processes.

Conclusion

In conclusion, Evplakin is a protein that is expressed in the ER and has been shown to play a role in the regulation of various cellular processes. Its potential as a drug target or biomarker makes it an attractive target for researchers to investigate further. The inhibition of Evplakin's activity could be a potential way to target this protein and its role in the regulation of protein synthesis and degradation. Further research is needed to fully understand the biology of Evplakin and its potential as a drug target or biomarker.

Protein Name: Envoplakin

Functions: Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments

The "EVPL Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about EVPL comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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