Target Name: PPP4C
NCBI ID: G5531
Review Report on PPP4C Target / Biomarker Content of Review Report on PPP4C Target / Biomarker
PPP4C
Other Name(s): protein phosphatase 4 catalytic subunit | Protein phosphatase X | epididymis secretory sperm binding protein | PPH3 | Serine/threonine-protein phosphatase 4 catalytic subunit | Serine/threonine-protein phosphatase 4 catalytic subunit (isoform 1) | PP4 | OTTHUMP00000162993 | PP4C_HUMAN | Protein phosphatase 4 catalytic subunit | Protein phosphatase 4 catalytic subunit, transcript variant 2 | protein phosphatase X, catalytic subunit | Protein phosphatase X, catalytic subunit | PPX | PPP4C variant 2 | Protein phosphatase 4 (formerly X), catalytic subunit | PP4C | PP-X | protein phosphatase 4 (formerly X), catalytic subunit | PPP4 | Pp4

Unlocking the Potential of PPP4C as a Drug Target and Biomarker

Protein phosphatases are a family of enzymes that play a crucial role in various cellular processes, including cell signaling, DNA replication, and metabolism. One of the best-known protein phosphatases is protein phosphatase 4 (PPP4C), an enzyme that is involved in the regulation of cellular processes that are crucial for cell survival and growth. Unfortunately, despite its importance, PPP4C has not yet been explored as a drug target or biomarker. In this article, we will explore the potential of PPP4C as a drug target and biomarker, and discuss the scientific evidence that supports this idea.

The Importance of Protein Phosphatases

Protein phosphatases are a group of enzymes that play a critical role in the regulation of protein function. These enzymes add a phosphate group to specific amino acids, which regulates various cellular processes, including cell signaling, DNA replication, and metabolism. PPP4C is one of the best-known protein phosphatases, and it is involved in the regulation of cellular processes that are crucial for cell survival and growth.

PPP4C is a protein that is expressed in various tissues and cells, including the brain, heart, liver, and muscle. It is involved in the regulation of several cellular processes, including cell signaling, cell division, and cell growth. PPP4C has been shown to be involved in the regulation of several cellular processes that are crucial for cell survival and growth, including:

1. Cell signaling: PPP4C is involved in the regulation of several signaling pathways that are crucial for cell survival and growth. For example, PPP4C has been shown to be involved in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cell signaling.
2. Cell division: PPP4C is involved in the regulation of cell division, including the G1 phase and the S phase.
3. Cell growth: PPP4C is involved in the regulation of cell growth, including the regulation of cell size and the cell cycle.

The Potential of PPP4C as a Drug Target

The potential of PPP4C as a drug target is based on several scientific evidence. First, several studies have shown that PPP4C is a validated drug target, with several potential drug compounds having been shown to interact with PPP4C. Second, several studies have shown that PPP4C is involved in the regulation of cellular processes that are crucial for human health, including the regulation of cancer progression and the regulation of inflammation.

PPP4C is also a good candidate for a biomarker due to its well-known role in cellular processes that are crucial for human health. The regulation of cellular processes that are crucial for human health is of great interest, as it is related to the development and progression of various diseases, including cancer and cardiovascular diseases.

The Potential of PPP4C as a Biomarker

PPP4C has the potential to serve as a biomarker for several diseases, including cancer and cardiovascular diseases. The regulation of cellular processes that are crucial for human health is of great interest, as it is related to the development and progression of various diseases. PPP4C is involved in the regulation of several cellular processes that are crucial for cell survival and growth, including cell signaling, cell division, and cell growth.

For example, several studies have shown that PPP4C is involved in the regulation of cancer progression. For instance, a study by Xu et al. showed that PPP4C was involved in the regulation of cancer cell migration and invasion. Another study by Zhang et al. showed that PPP4C was involved in the regulation of

Protein Name: Protein Phosphatase 4 Catalytic Subunit

Functions: Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, DNA repair, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AX phosphorylated on Ser-140 (gamma-H2AX) generated during DNA replication and required for DNA double strand break repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). In response to DNA damage, catalyzes RPA2 dephosphorylation, an essential step for DNA repair since it allows the efficient RPA2-mediated recruitment of RAD51 to chromatin

The "PPP4C Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PPP4C comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PPP4R1 | PPP4R1-AS1 | PPP4R1L | PPP4R2 | PPP4R3A | PPP4R3B | PPP4R3C | PPP4R4 | PPP5C | PPP5D1P | PPP6C | PPP6R1 | PPP6R2 | PPP6R2P1 | PPP6R3 | PPRC1 | PPT1 | PPT2 | PPT2-EGFL8 | PPTC7 | PPWD1 | PPY | PPY2P | PQBP1 | PRAC1 | PRAC2 | PRADC1 | PRAF2 | PRAG1 | PRAM1 | PRAME | PRAMEF1 | PRAMEF10 | PRAMEF11 | PRAMEF12 | PRAMEF14 | PRAMEF15 | PRAMEF16 | PRAMEF17 | PRAMEF18 | PRAMEF19 | PRAMEF2 | PRAMEF20 | PRAMEF22 | PRAMEF27 | PRAMEF29P | PRAMEF3 | PRAMEF36P | PRAMEF4 | PRAMEF5 | PRAMEF6 | PRAMEF7 | PRAMEF8 | PRAMEF9 | PRANCR | PRAP1 | PRB1 | PRB2 | PRB3 | PRB4 | PRC1 | PRC1-AS1 | PRCC | PRCD | PRCP | PRDM1 | PRDM10 | PRDM10-DT | PRDM11 | PRDM12 | PRDM13 | PRDM14 | PRDM15 | PRDM16 | PRDM16-DT | PRDM2 | PRDM4 | PRDM5 | PRDM6 | PRDM7 | PRDM8 | PRDM9 | PRDX1 | PRDX2 | PRDX2P4 | PRDX3 | PRDX4 | PRDX5 | PRDX6 | Pre-mRNA cleavage complex II | PREB | PRECSIT | Prefoldin complex | PRELID1 | PRELID1P6 | PRELID2 | PRELID3A | PRELID3B | PRELP | Prenyl diphosphate synthase