Target Name: HPCA
NCBI ID: G3208
Review Report on HPCA Target / Biomarker Content of Review Report on HPCA Target / Biomarker
HPCA
Other Name(s): Neuron specific calcium-binding protein hippocalcin | DYT2 | Neuron-specific calcium-binding protein hippocalcin | dystonia 2 | Hippocalcin | Calcium-binding protein BDR-2 | calcium-binding protein BDR-2 | torsion (autosomal recessive) | dystonia 2, torsion (autosomal recessive) | BDR2 | hippocalcin | HPCA_HUMAN

HPCA: A Protein with Potential as A Drug Target and Biomarker

HPCA, or Hippocalcin, is a protein that is expressed in the brain and is known for its role in the regulation of neural signaling. It is a type of calcium-binding protein, which means that it interacts with calcium ions in the brain.

Hippocalcin has been shown to play a role in a number of neural processes, including the regulation of neuronal communication and the control of neurotransmitter release. It is also involved in the regulation of pain perception and the treatment of anxiety disorders.

One of the key benefits of HPCA is its ability to selectively interact with certain types of neurons, rather than all neurons in the brain. This allows researchers to target specific populations of neurons and study their behavior in greater detail.

One potential use for HPCA as a drug target is its role in the regulation of pain. Chronic pain is a significant public health issue, with estimates suggesting that it affects more than 100 million people in the United States alone.

Studies have shown that HPCA is involved in the regulation of pain perception and the production of pain signals. By targeting HPCA, researchers may be able to develop new treatments for chronic pain.

Another potential use for HPCA is its role in the regulation of neurotransmission. Neurons communicate with one another through the release of chemical messengers, called neurotransmitters. The release of these messengers is regulated by a complex system of proteins, including HPCA.

Research has shown that HPCA plays a role in the regulation of neurotransmission, including the release of neurotransmitters such as dopamine and serotonin. This suggests that HPCA may be an attractive target for drugs that are designed to modulate neurotransmission.

In addition to its potential as a drug target, HPCA also has potential as a biomarker. The regulation of neural signaling is a complex process, and the expression of different genes and proteins can vary depending on the specific context.

Studies have shown that HPCA is expressed in a variety of neural tissues and is involved in the regulation of a wide range of neural processes. This makes it an attractive candidate for use as a biomarker for a variety of neural disorders, including neurological and psychiatric conditions.

Overall, HPCA is a protein that has significant potential as a drug target and as a biomarker. Its ability to selectively interact with certain types of neurons and its involvement in the regulation of neural signaling make it an attractive candidate for further research and development.

Protein Name: Hippocalcin

Functions: Calcium-binding protein that may play a role in the regulation of voltage-dependent calcium channels (PubMed:28398555). May also play a role in cyclic-nucleotide-mediated signaling through the regulation of adenylate and guanylate cyclases (By similarity)

The "HPCA Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HPCA comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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