Meak7: A Potential Drug Target and Biomarker for Various Diseases

Target Name: MEAK7

NCBI ID: G57707

MEAK7

Meak7: A Potential Drug Target and Biomarker for Various Diseases

Meak7 (TBC/LysM-associated domain containing 1) is a protein that has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It is a member of the superfamily of leucine-rich repeat (LRR) proteins, which are characterized by the presence of a leucine-rich repeat in their amino acid sequence. Meak7 is expressed in a variety of tissues and cells, including brain, heart, liver, and muscle, and has been shown to play a role in various cellular processes, including cell signaling, protein synthesis, and stress response.

Disease association

Meak7 has been associated with a number of diseases and disorders, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, studies have shown that Meak7 is overexpressed in various types of cancer, including breast, ovarian, and colorectal cancer. This suggests that targeting Meak7 may be a promising strategy for the development of new cancer therapies. Additionally, Meak7 has been shown to be involved in the development and progression of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease.

Autism

Meak7 has also been linked to autism, a neurodevelopmental disorder that affects millions of people worldwide. Studies have shown that Meak7 is expressed in the brain and that it is involved in the development of autism-like behaviors in animal models of the disease. Additionally, people with certain forms of autism are characterized by the loss of Meak7, which suggests that this protein may play a role in the development and progression of autism.

Other diseases

Meak7 has also been associated with a number of other diseases and disorders, including heart disease, liver disease, and stress response. For example, studies have shown that Meak7 is involved in the regulation of cellular stress responses and that it plays a role in the development of heart disease. Additionally, Meak7 has been shown to be involved in the regulation of protein synthesis and has been linked to the development of liver disease.

Potential drug targets

Given the association of Meak7 with a number of diseases and disorders, it is a promising target for drug development. Studies have shown that Meak7 can be targeted with small molecules, antibodies, and other therapeutic agents. For example, studies have shown that inhibiting Meak7 can protect against neurodegenerative diseases, including Alzheimer's disease, in animal models of the disease. Additionally, antibodies against Meak7 have been shown to be effective in treating certain forms of cancer, including breast cancer.

Biomarker potential

Meak7 has also been identified as a potential biomarker for a number of diseases and disorders. For example, studies have shown that Meak7 is involved in the regulation of cellular stress responses and that it can be used as a biomarker for stress response disorders, such as anxiety and depression. Additionally, Meak7 has been shown to be involved in the regulation of protein synthesis and has been linked to the development of various diseases, including cancer and neurodegenerative disorders. This suggests that Meak7 may be a useful biomarker for these diseases and for monitoring the effectiveness of therapeutic interventions.

Conclusion

Meak7 (TBC/LysM-associated domain containing 1) is a protein that has been identified as a potential drug target or biomarker for a number of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. It is a member of the superfamily of leucine-rich repeat (LRR) proteins and is expressed in a variety of tissues and cells. Meak7 has been associated with a number of diseases and disorders, including cancer, neurodegenerative diseases, and autoimmune disorders. Studies have shown that Meak7 can be targeted with small molecules, antibodies, and other therapeutic agents and that it may be a useful

Protein Name: MTOR Associated Protein, Eak-7 Homolog

Functions: Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193). Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193)

The "MEAK7 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MEAK7 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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