SELP: A Protein with Potential as A Drug Target Or Biomarker (G6403)

Target Name: SELP

NCBI ID: G6403

SELP

SELP: A Protein with Potential as A Drug Target Or Biomarker

SELP (sP-selectin_(HUMAN)) is a protein that is expressed in various tissues of the human body, including the skin, hair, nails, and connective tissues. It is a member of the selectin family, which is a group of proteins that are involved in cell-cell and cell-extracellular matrix interactions.

One of the unique features of SELP is its ability to interact with integrins, which are a type of protein that is found on the surface of many cells. Integrins are involved in many different processes in the body, including cell adhesion, migration, and signaling. By interacting with integrins, SELP is able to regulate the movement and behavior of cells, which can be important for a wide range of biological processes.

SELP has also been shown to play a role in the development and progression of various diseases, including cancer. For example, studies have shown that high levels of SELP are associated with poor prognosis in patients with skin cancer. Additionally, SELP has been shown to be involved in the regulation of the immune response, which is important for protecting the body against the spread of infection and disease.

Despite these promising findings, much more research is needed about SELP and its role in the body. One of the main challenges in studying SELP is its complex structure, as it is difficult to purify and study the protein in a controlled environment. Additionally, the functions of SELP are not well understood, which makes it difficult to predict how it might be used as a drug target or biomarker.

In conclusion, SELP is a protein that has the potential to be a drug target or biomarker due to its unique structure and involvement in various biological processes. Further research is needed to fully understand its functions and potential uses in the body.

Protein Name: Selectin P

Functions: Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG

The "SELP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SELP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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