BTBD18: A Protein Involved in Cell Signaling and Cancer Development

Target Name: BTBD18

NCBI ID: G643376

BTBD18

Other Name(s): BTB (POZ) domain containing 18 | hCG1730474 | BTB domain containing 18 | BTB/POZ domain-containing protein 18 | BTBDI_HUMAN

BTBD18: A Protein Involved in Cell Signaling and Cancer Development

BTBD18 (BTB (POZ) domain containing 18) is a protein that is expressed in various tissues of the human body. It is a member of the BTB protein family, which is known for their role in intracellular signaling. BTBD18 is characterized by the presence of a POZ domain, which is a unique type of protein domain that is found in a variety of organisms and is involved in protein-protein interactions.

The BTB protein family is involved in a wide range of cellular processes, including cell signaling, DNA replication, and protein degradation. BTBD18 is specifically involved in the regulation of cell adhesion and in the development of cancer.

Studies have suggested that BTBD18 may be a drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. For example, some researchers have found that high levels of BTBD18 are associated with an increased risk of developing pancreatic cancer, and that inhibiting BTBD18 may be a promising strategy for treating this disease.

In addition to its potential as a drug target, BTBD18 has also been identified as a potential biomarker for a variety of diseases. For example, some studies have found that BTBD18 is expressed in the brains of individuals with Alzheimer's disease, and that levels of BTBD18 are associated with the severity of this disease. Other researchers have also found that BTBD18 is expressed in the livers of individuals with liver cancer, and that high levels of BTBD18 may be a useful biomarker for this disease.

Despite the potential for BTBD18 as a drug target or biomarker, more research is needed to fully understand its role in these processes. Additionally, the study of BTBD18 may also be relevant to the study of other proteins that are involved in intracellular signaling, as well as the development of new therapeutic strategies for a variety of diseases.

Protein Name: BTB Domain Containing 18

Functions: Specifically required during spermatogenesis to promote expression of piRNA precursors. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Acts by facilitating transcription elongation at piRNA loci during pachytene

The "BTBD18 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BTBD18 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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