HHIP: A Protein Regulator of Cell Signaling and Development (G64399)

Target Name: HHIP

NCBI ID: G64399

HHIP

Other Name(s): Hedgehog-interacting protein | HIP | hedgehog interacting protein | Hedgehog interacting protein | HHIP_HUMAN

HHIP: A Protein Regulator of Cell Signaling and Development

Hedgehog-interacting protein (HHIP) is a protein that plays a crucial role in cell signaling and development. It is a key regulator of the Wnt signaling pathway, a well-established pathway that regulates cell growth, differentiation, and survival. HHIP is a 26-kDa protein that is expressed in a variety of tissues, including nervous system, endothelial system, and various organs. It has been implicated in a wide range of biological processes, including cell survival, angiogenesis, and tissue repair.

One of the unique features of HHIP is its ability to interact with the protein Shh, which is a key regulator of the Wnt signaling pathway. The Wnt signaling pathway is a critical pathway that regulates cell growth and development, and it is involved in the development and maintenance of tissues and organs. HHIP has been shown to play a critical role in the regulation of Wnt signaling by Shh, and it is a potential drug target or biomarker for a variety of diseases.

HHIP has been shown to regulate the activity of various cellular signaling pathways that are involved in cell growth, differentiation, and survival. For example, HHIP has been shown to play a role in the regulation of the PI3K/Akt signaling pathway, which is involved in the regulation of cell survival and angiogenesis. Additionally, HHIP has been shown to regulate the TGF-β signaling pathway, which is involved in the regulation of cell growth and differentiation.

HHIP has also been shown to play a role in the regulation of cell adhesion and migration. For example, HHIP has been shown to interact with the protein Focal Adhesion Protein (FAP), which is involved in the regulation of cell adhesion and migration. Additionally, HHIP has been shown to play a role in the regulation of cell survival and angiogenesis, which is critical for the development and maintenance of tissues and organs.

HHIP has also been shown to play a role in the regulation of inflammation and immune responses. For example, HHIP has been shown to interact with the protein NF-kappa-B, which is involved in the regulation of inflammation and immune responses. Additionally, HHIP has been shown to play a role in the regulation of cell signaling pathways that are involved in cancer progression and metastasis.

In conclusion, HHIP is a protein that plays a critical role in the regulation of cell signaling and development. It is a potential drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Further research is needed to fully understand the role of HHIP in various biological processes and to develop effective treatments based on its properties.

Protein Name: Hedgehog Interacting Protein

Functions: Modulates hedgehog signaling in several cell types including brain and lung through direct interaction with members of the hedgehog family

The "HHIP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about HHIP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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