LOC729218: A Potential Drug Target for Cancer and Autoimmune Disorders

Target Name: LOC729218

NCBI ID: G729218

LOC729218

Other Name(s): uncharacterized LOC729218 | Uncharacterized LOC729218, transcript variant 1

LOC729218: A Potential Drug Target for Cancer and Autoimmune Disorders

LOC729218 is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and kidneys. It is a member of the T-cell antigen receptor (TCR) family, which is a type of receptor that is expressed on the surface of immune cells, including T-cells. LOC729218 is also known as UNC-6176, and it has been identified as a potential drug target in several diseases.

The TCR is a transmembrane protein that is composed of a variable region and a constant region. The variable region of the TCR is responsible for recognizing specific antigens, while the constant region provides the structural stability of the receptor. LOC729218 is a 21-kDa protein that is expressed in the brain, heart, liver, and kidneys. It is characterized by a constant region that contains a single transmembrane domain and a cytoplasmic tail.

LOC729218 is involved in the immune response by regulating the activity of T-cells. T-cells are a type of immune cell that play a critical role in protecting the body against infection and disease. LOC729218 is known to be involved in the regulation of T-cell activation, proliferation, and differentiation.

One of the functions of LOC729218 is to regulate the activity of T-cells that are involved in cancer. Several studies have shown that LOC729218 is expressed in various types of cancer, including breast, lung, and colon cancer. Additionally, LOC729218 has been shown to promote the growth and survival of cancer cells in cell culture and animal models.

Another function of LOC729218 is to regulate the immune response by limiting the activity of immune cells. This is done by regulating the activation and proliferation of T-cells, as well as the production of antibodies. LOC729218 has been shown to block the activity of T-cells that are involved in immune surveillance, which may contribute to the immune privilege in cancer.

LOC729218 has also been shown to be involved in the regulation of inflammation. Inflammation is a natural response of the immune system to injury or infection, but chronic inflammation can contribute to a variety of diseases, including heart disease, diabetes, and rheumatoid arthritis. LOC729218 has been shown to regulate the production of pro-inflammatory cytokines, which are involved in the regulation of inflammation.

In conclusion, LOC729218 is a protein that is involved in the immune response and inflammation. Its functions include regulating the activity of T-cells, blocking the immune surveillance in cancer, and regulating the production of pro-inflammatory cytokines. These functions make LOC729218 a potential drug target for a variety of diseases, including cancer and autoimmune disorders. Further research is needed to fully understand the role of LOC729218 in the immune response and disease.

Protein Name: Uncharacterized LOC729218

The "LOC729218 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC729218 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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