Target Name: WNK1
NCBI ID: G65125
Review Report on WNK1 Target / Biomarker Content of Review Report on WNK1 Target / Biomarker
WNK1
Other Name(s): protein kinase with no lysine 1 | Erythrocyte 65 kDa protein | protein phosphatase 1, regulatory subunit 167 | PSK | Serine/threonine-protein kinase WNK1 (isoform 1) | KIAA0344 | PRKWNK1 | Serine/threonine-protein kinase WNK1 (isoform 4) | Protein kinase lysine-deficient 1 | WNK1 variant 1 | WNK1 variant 4 | Kinase deficient protein | Serine/threonine-protein kinase WNK1 | Prostate-derived sterile 20-like kinase | Protein kinase with no lysine 1 | WNK lysine deficient protein kinase 1 isoform | Serine/threonine-protein kinase WNK1 (isoform 3) | PPP1R167 | WNK lysine deficient protein kinase 1 (WNK1) | erythrocyte 65 kDa protein | WNK lysine deficient protein kinase 1, transcript variant 1 | Protein phosphatase 1, regulatory subunit 167 | WNK1_HUMAN | prostate-derived sterile 20-like kinase | P65 | p65 | WNK1 variant 3 | HSAN2 | WNK lysine deficient protein kinase 1, transcript variant 4 | KDP | HSN2 | PHA2C | Protein kinase, lysine deficient 1 | WNK lysine deficient protein kinase 1, transcript variant 3 | serine/threonine-protein kinase WNK1 | serine/threonine-protein kinase WNK1 1 | hWNK1 | WNK lysine deficient protein kinase 1 | serine/threonine-protein kinase WNK1 2

WNK1: A Non-Code RNA Molecule Involved in Cell Growth, Differentiation and Survival

Protein kinase with no lysine 1 (WNK1) is a protein that plays a critical role in various cellular processes. It is a non-coding RNA molecule that is expressed in various tissues and cells. WNK1 is known to be involved in the regulation of cell growth, differentiation, and survival. It is also associated with the development and progression of many diseases, including cancer. As a result, WNK1 has become an attractive drug target for researchers to explore.

WNK1 is a protein that is known to be involved in the regulation of cell growth and differentiation. It is a non-coding RNA molecule that is expressed in various tissues and cells. It is made up of 196 amino acids and has a calculated molecular mass of 21.1 kDa. WNK1 is highly conserved, with only one known isoform. It is expressed in various tissues, including the brain, heart, skeletal muscles, and tissues of the reproductive system.

WNK1 is involved in the regulation of cell growth and differentiation by controlling the activity of several transcription factors. It is known to be a negative regulator of the run-on gene, which encodes the RNA polymerase II (RPN) subunit. The RPN is a key enzyme that is involved in the regulation of gene expression, and it is thought to play a crucial role in the development and progression of cancer. WNK1 is also known to be a positive regulator of the p53 gene, which encodes the tumor suppressor protein p53 . The p53 gene is known to be involved in the regulation of cell growth and differentiation, and it is thought to play a crucial role in the development and progression of cancer.

WNK1 is involved in the regulation of cell survival by controlling the activity of several pro-apoptotic enzymes. These enzymes are responsible for causing the death of cells when they reach certain sizes, which is a critical check on cell growth. WNK1 is known to be a negative regulator of the Bcl-2 gene, which encodes the protein Bcl-2. The Bcl-2 gene is thought to be involved in the regulation of cell survival, and it is thought to play a crucial role in the development and progression of cancer. WNK1 is also known to be a positive regulator of the p53 gene, which encodes the tumor suppressor protein p53. The p53 gene is known to be involved in the regulation of cell growth and differentiation, and it is thought to play a crucial role in the development and progression of cancer.

WNK1 is involved in the regulation of cell signaling by controlling the activity of several protein kinases. These enzymes are responsible for catalyzing the transfer of chemical groups from one protein to another, which is a critical step in many signaling pathways. WNK1 is known to be a negative regulator of the TCF-1 gene, which encodes the transcription factor TCF-1. The TCF-1 gene is known to be involved in the regulation of cell signaling, and it is thought to play a crucial role in the development and progression of cancer. WNK1 is also known to be a positive regulator of the p300 gene, which encodes the protein p300. The p300 gene is thought to be involved in the regulation of cell signaling, and it is thought to play a crucial role in the development and progression of cancer.

WNK1 is involved in the regulation of cell inflammation by controlling the activity of several cytokines. These hormones are responsible for causing inflammation in response to various stimuli, and they play a crucial role in the development and progression of many diseases, including cancer. WNK1 is known to be a negative regulator of the IL-6 gene, which encodes the cytokine interleukin-6 (IL-6). The IL-6 gene is

Protein Name: WNK Lysine Deficient Protein Kinase 1

Functions: Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide-sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L. Acts as a scaffold to inhibit SLC4A4, SLC26A6 as well as CFTR activities and surface expression, recruits STK39 which mediates the inhibition (By similarity)

The "WNK1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WNK1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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WNK2 | WNK3 | WNK4 | Wnt | WNT1 | WNT10A | WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N | XPA | XPC | XPC complex | XPNPEP1 | XPNPEP2 | XPNPEP3 | XPO1 | XPO4 | XPO5 | XPO6 | XPO7 | XPOT | XPR1 | XRCC1 | XRCC2 | XRCC3 | XRCC4 | XRCC5