WNT10A: A Potential Drug Target and Biomarker (G80326)
WNT10A: A Potential Drug Target and Biomarker
Wnt-10a, also known as WNT10A, is a non-coding RNA molecule that plays a crucial role in the development and maintenance of various tissues, including neural cells and cancer cells. It is a key regulator of the Wnt signaling pathway, which is a well-established mechanism for the development and progression of many diseases, including cancer.
The Wnt signaling pathway is a complex signaling pathway that is involved in the regulation of cell proliferation, differentiation, and survival. It is a highly conserved pathway that is highly conserved across many different species, including humans. The pathway is composed of several proteins, including Wnt1, Wnt3, Wnt5, and Wnt6, which are involved in the regulation of cell surface interactions and the formation of the Wnt-10 complex.
Wnt-10a is a key regulator of the Wnt-10 complex, which is composed of the proteins Wnt10a, Wnt10b, and Wnt10c. Wnt-10a functions as a negative regulator of the Wnt10b/Wnt10c complex, which is responsible for the regulation of cell proliferation and differentiation.
One of the key functions of Wnt-10a is its role in the regulation of stem cell proliferation. stem cells are a type of cell that have the ability to self-renew and differentiate into many different cell types, including neural cells. stem cell proliferation is critical for the development and maintenance of tissues and organs, including neural cells.
Wnt-10a is also involved in the regulation of cancer cell proliferation. Cancer cells are able to evade the normal cell cycle and continue to divide and proliferate uncontrollably. The regulation of cell proliferation is a critical aspect of cancer development, and Wnt-10a is involved in this regulation.
In addition to its role in cell proliferation, Wnt-10a is also involved in the regulation of cell survival. There are many studies showing that Wnt-10a plays a role in the regulation of cell survival by preventing apoptosis. Apoptosis is a natural form of cell death that is regulated by a variety of factors, including Wnt signaling pathway.
Wnt-10a is also involved in the regulation of cell migration. Cell migration is a critical aspect of tissue development and repair, and it is regulated by a variety of factors, including Wnt signaling pathway.
Due to its involvement in so many critical aspects of cell biology, Wnt-10a is a potential drug target and biomarker. Many studies have identified potential small molecules that can inhibit the activity of Wnt-10a, and these compounds have been shown to have a variety of therapeutic effects, including the inhibition of cancer cell proliferation and the regulation of neural cell survival.
In conclusion, Wnt-10a is a non-coding RNA molecule that plays a crucial role in the development and maintenance of various tissues, including neural cells and cancer cells. It is a key regulator of the Wnt signaling pathway and is involved in the regulation of cell proliferation, differentiation, and survival. As a potential drug target and biomarker, Wnt-10a is a promising target for the development of new therapies for a variety of diseases.
Protein Name: Wnt Family Member 10A
Functions: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway (By similarity). Plays a role in normal ectoderm development (PubMed:17847007, PubMed:28589954). Required for normal tooth development (PubMed:17847007, PubMed:29178643, PubMed:28589954). Required for normal postnatal development and maintenance of tongue papillae and sweat ducts (PubMed:28589954). Required for normal proliferation of basal cells in tongue filiform papillae, plantar epithelium and sweat ducts. Required for normal expression of keratins in tongue papillae (By similarity). Required for normal expression of KRT9 in foot plant epithelium (PubMed:28589954). Required for normal hair follicle function (PubMed:28589954)
The "WNT10A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about WNT10A comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
WNT10B | WNT11 | WNT16 | WNT2 | WNT2B | WNT3 | WNT3A | WNT4 | WNT5A | WNT5B | WNT6 | WNT7A | WNT7B | WNT8A | WNT8B | WNT9A | WNT9B | WRAP53 | WRAP73 | WRN | WRNIP1 | WSB1 | WSB2 | WSCD1 | WSCD2 | WSPAR | WT1 | WT1-AS | WTAP | WTAPP1 | WTIP | WWC1 | WWC2 | WWC2-AS2 | WWC3 | WWOX | WWP1 | WWP2 | WWTR1 | WWTR1-AS1 | XAB2 | XACT | XAF1 | XAGE-4 | XAGE1A | XAGE1B | XAGE1D | XAGE2 | XAGE3 | XAGE5 | XBP1 | XCL1 | XCL2 | XCR1 | XDH | XG | XGY2 | XIAP | XIRP1 | XIRP2 | XIST | XK | XKR3 | XKR4 | XKR5 | XKR6 | XKR7 | XKR8 | XKR9 | XKRX | XKRY | XKRYP7 | XLOC_007697 | XLOC_008559 | XLOC_009911 | XNDC1N | XPA | XPC | XPC complex | XPNPEP1 | XPNPEP2 | XPNPEP3 | XPO1 | XPO4 | XPO5 | XPO6 | XPO7 | XPOT | XPR1 | XRCC1 | XRCC2 | XRCC3 | XRCC4 | XRCC5 | XRCC6 | XRCC6P5 | XRN1 | XRN2 | XRRA1 | XXYLT1
