SLC39A2: Potential Drug Targets Or Biomarkers for Uncontrolled Processes

Target Name: SLC39A2

NCBI ID: G29986

SLC39A2

SLC39A2: Potential Drug Targets Or Biomarkers for Uncontrolled Processes

SLC39A2 is a member of the SLC39 family, which is a well-established transmembrane protein family that plays a central role in various physiological processes in the body. SLC39A2 is a 39-kDa protein that is expressed in various tissues and cells in the body, including the brain, heart, and kidneys. Its function in these cells is still not well understood, but research has shown that it plays a significant role in various physiological processes, including cellular signaling, ion transport, and modulating gene expression.

One of the key functions of SLC39A2 is its role in modulating gene expression. SLC39A2 has been shown to interact with various transcription factors, including activator protein 1 (AP-1), which is a key transcription factor that regulates cell proliferation and survival. SLC39A2 has been shown to physically interact with AP-1 and to modulate its activity. This interaction between SLC39A2 and AP-1 suggests that SLC39A2 may be a drug target or biomarker for diseases that are characterized by uncontrolled cell proliferation, such as cancer.

Another function of SLC39A2 is its role in cellular signaling. SLC39A2 has been shown to play a role in the regulation of cellular signaling pathways, including the TGF-β pathway. TGF-β is a well-established signaling pathway that regulates cellular growth, differentiation, and survival, and its activity is critical for the development and maintenance of tissues and organs. SLC39A2 has been shown to regulate the activity of the TGF-β pathway by modulating the activity of various transcription factors, including AP-1. This interaction between SLC39A2 and AP-1 suggests that SLC39A2 may be a drug target or biomarker for diseases that are characterized by uncontrolled cellular growth and differentiation, such as cancer.

In addition to its role in modulating gene expression and cellular signaling, SLC39A2 has also been shown to play a role in the regulation of ion transport. SLC39A2 is a member of the Na+/K+ ATPase (NaKATPase) gene family, which is responsible for regulating the movement of Na+ and K+ ions across the cell membrane. This function is critical for maintaining the resting membrane potential of the cell and for regulating various physiological processes, including muscle contractions and neural activity. SLC39A2 has been shown to regulate the activity of the NaKATPase gene by modulating its activity, which suggests that it may be a drug target or biomarker for diseases that are characterized by abnormal ion transport, such as heart failure.

Finally, SLC39A2 has also been shown to play a role in modulating the structure and function of the brain. SLC39A2 is expressed in various tissues and cells of the brain, including the prefrontal cortex, which is responsible for various higher-order cognitive functions. SLC39A2 has been shown to play a role in the regulation of the structure and function of the brain by modulating the activity of various transcription factors, including Dlx1. This interaction between SLC39A2 and Dlx1 suggests that SLC39A2 may be a drug target or biomarker for diseases that are characterized by abnormal brain development or function, such as Alzheimer's disease.

In conclusion, SLC39A2 is a well-established transmembrane protein that plays a central role in various physiological processes in the body. Its function in modulating gene expression, cellular signaling, ion transport, and modulating the structure and function of the brain suggests that it may be a drug target or biomarker for a variety of diseases. Further research is needed to fully understand the role of SLC39A2 in these diseases and to develop effective treatments.

Protein Name: Solute Carrier Family 39 Member 2

Functions: Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis

The "SLC39A2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC39A2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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