Target Name: SLC30A10
NCBI ID: G55532
Review Report on SLC30A10 Target / Biomarker Content of Review Report on SLC30A10 Target / Biomarker
SLC30A10
Other Name(s): DKFZp547M236 | ZNT10_HUMAN | Zinc transporter 10 | Zinc transporter 10 (isoform 1) | Solute carrier family 30 (zinc transporter), member 10 | solute carrier family 30 member 10 | Zinc transporter 8 | Manganese transporter SLC30A10 | Solute carrier family 30 member 10, transcript variant 1 | HMNDYT1 | ZNT10 | manganese transporter SLC30A10 | Solute carrier family 30 member 10 (SLC30A10) | SLC30A10 variant 1 | ZnT-10 | ZNT8 | Solute carrier family 30 member 10 | zinc resistance conferring homolog | ZRC1 | HMDPC | zinc transporter 8

SLC30A10: A Protein Involved in Cell Membrane Transport and Disease Development

SLC30A10 (DKFZp547M236) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the SLC30 family of transmembrane proteins, which are known for their ability to transport a variety of molecules across the cell membrane. SLC30A10 is also known as DKFZp547M236 because it is a derivative of the DKFZ gene, which is located on chromosome 18.

SLC30A10 is involved in a number of physiological processes in the body, including the regulation of ion and water balance, as well as the transport of various molecules across cell membranes. It is also involved in the development and maintenance of various tissues, including the brain and heart.

SLC30A10 has been shown to play a role in a number of diseases and conditions, including cancer, neurodegenerative diseases, and kidney disease. It is often used as a drug target or biomarker because of its involvement in these processes.

One of the main functions of SLC30A10 is its role in the regulation of ion and water balance. This is important for maintaining the proper functioning of various tissues and organs, including the brain and heart. SLC30A10 helps to regulate the movement of ions and water molecules across the cell membrane, ensuring that these molecules are properly balanced and that the cell remains in a stable state.

In addition to its role in ion and water balance, SLC30A10 is also involved in the regulation of the development and maintenance of various tissues. For example, it has been shown to play a role in the development and maintenance of the brain, heart, and kidneys. SLC30A10 is also involved in the regulation of cell growth and division, as well as in the formation of various tissues and organs.

SLC30A10 has also been shown to be involved in the development and progression of a number of diseases and conditions, including cancer and neurodegenerative diseases. For example, studies have shown that high levels of SLC30A10 are associated with an increased risk of certain cancers, such as breast and ovarian cancer. Additionally, SLC30A10 has been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.

Despite its involvement in a number of important physiological processes and its association with a number of diseases and conditions, SLC30A10 is not yet widely studied or understood. There is a need for further research to better understand the role of SLC30A10 in these processes and to develop better treatments for those who are affected by these conditions.

In conclusion, SLC30A10 is a protein that is involved in a number of important physiological processes and has been shown to play a role in the development and maintenance of various tissues. While more research is needed to fully understand its role in these processes and to develop better treatments for those who are affected by its association with disease, SLC30A10 is an promising drug target or biomarker with potential for the development of new treatments for a variety of conditions.

Protein Name: Solute Carrier Family 30 Member 10

Functions: Calcium:manganese antiporter of the plasma membrane mediating the efflux of intracellular manganese coupled to an active extracellular calcium exchange (PubMed:30755481). Required for intracellular manganese homeostasis, an essential cation for the function of several enzymes, including some crucially important for the metabolism of neurotransmitters and other neuronal metabolic pathways. Manganese can also be cytotoxic and induce oxidative stress, mitochondrial dysfunction and apoptosis (PubMed:22341972, PubMed:25319704, PubMed:27226609, PubMed:27307044, PubMed:26728129). Could also have an intracellular zinc ion transporter activity, directly regulating intracellular zinc ion homeostasis and more indirectly various signaling pathway and biological processes (PubMed:22427991, PubMed:26728129)

The "SLC30A10 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC30A10 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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