GLUT-8: A Protein Involved in Cell Adhesion, Migration and Blood Sugar Regulation

Target Name: SLC2A8

NCBI ID: G29988

SLC2A8

GLUT-8: A Protein Involved in Cell Adhesion, Migration and Blood Sugar Regulation

GLUT-8, also known as SLC2A8, is a protein that is expressed in most tissues of the body. It is a member of the GLUT family, which includes several related proteins that are involved in glucose transport and metabolism. One of the main functions of GLUT-8 is to regulate the movement of glucose into and out of cells. This protein plays a crucial role in the regulation of blood sugar levels, and it is often used as a drug target or biomarker for various diseases.

GLUT-8 is a 21-kDa protein that is expressed in most tissues of the body. It is synthesized in the liver and pancreas, and it is mainly targeted to the endoplasmic reticulum (ER) and the cytoplasm. GLUT-8 is involved in the regulation of several cellular processes, including cell adhesion, migration, and the transport of nutrients and waste products.

One of the main functions of GLUT-8 is to regulate the movement of glucose into and out of cells. This is accomplished through its interaction with several other proteins, including GLUT-1, GLUT-2, and GLUT-4. GLUT-1 and GLUT-2 are also known as the GLUT-4-GLUT-1 complex, and they are involved in the regulation of insulin sensitivity and glucose metabolism. GLUT-4 is a protein that is highly expressed in the liver and pancreas, and it is involved in the regulation of glucose metabolism, including the transport of glucose into the liver.

GLUT-8 is also involved in the regulation of cell adhesion and migration. This is accomplished through its interaction with several other proteins, including N-cadherin and vimentin. N-cadherin is a transmembrane protein that is involved in cell-cell adhesion, while vimentin is a microtubule protein that is involved in cell migration. GLUT-8 helps to regulate the movement of these proteins into the cell, which is necessary for the formation and maintenance of tissues and organs.

GLUT-8 is also involved in the regulation of several cellular processes that are important for overall cellular health and function. This includes the regulation of cell cycle progression, DNA replication, and apoptosis. GLUT-8 helps to regulate the movement of proteins that are involved in these processes into the cell, which is necessary for the proper functioning of the cell.

In addition to its role in regulating cellular processes, GLUT-8 is also a potential drug target or biomarker for several diseases. For example, GLUT-8 has been shown to be involved in the regulation of insulin sensitivity, which is a risk factor for several diseases, including type 2 diabetes. Additionally, GLUT-8 has been shown to be involved in the regulation of inflammation, which is a risk factor for several diseases, including heart disease and cancer.

GLUT-8 is also a potential biomarker for several diseases, including cancer. This is because it is often expressed in cancer cells, and its levels can be used as a diagnostic marker for some types of cancer. For example, GLUT-8 has been shown to be expressed in several types of cancer, including breast cancer, lung cancer, and colorectal cancer. This suggests that GLUT-8 may be a useful biomarker for the diagnosis and treatment of these diseases.

In conclusion, GLUT-8 is a protein that is involved in several cellular processes that are important for overall cellular health and function. It is expressed in most tissues of the body and plays a crucial role in the regulation of blood sugar levels, as well as the regulation of cell adhesion, migration, and the transport of nutrients and waste products. GLUT-8 is also involved in the regulation of insulin sensitivity and inflammation, and it is a potential drug target or biomarker for several diseases. Further research is needed to fully understand the role of GLUT-8 in these processes and to develop effective treatments for these diseases.

Protein Name: Solute Carrier Family 2 Member 8

Functions: Insulin-regulated facilitative hexose transporter that mediates the transport of glucose and fructose. Also able to mediate the transport of dehydroascorbate

The "SLC2A8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SLC2A8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets