SLC35B1: A Protein Regulating Bile Ducts and TGF-?? Signaling

Target Name: SLC35B1

NCBI ID: G10237

SLC35B1

SLC35B1: A Protein Regulating Bile Ducts and TGF-?? Signaling

SLC35B1 (UGTREL1) is a protein that is expressed in various tissues throughout the body, including the brain, heart, liver, and pancreas. It is a member of the superfamily of transmembrane protein (SMP) family and is characterized by the presence of a unique transmembrane region and a cytoplasmic tail.

SLC35B1 is a protein that is known to play a critical role in the regulation of various physiological processes that are dependent on the function of the liver. Specifically, it is involved in the detoxification and metabolism of a wide variety of drugs, including many drugs that are used to treat human diseases.

SLC35B1 is also involved in the regulation of cellular signaling pathways that are important for the development and maintenance of tissues and organs. One of the key signaling pathways that is regulated by SLC35B1 is the NF-kappa pathway, which is a well-established pathway that is involved in the regulation of cell growth, differentiation, and survival.

SLC35B1 is also involved in the regulation of the Wnt signaling pathway, which is a critical pathway that is involved in the development and maintenance of tissues and organs. The Wnt signaling pathway is a highly conserved signaling pathway that is involved in the regulation of a wide variety of cellular processes, including cell growth, differentiation, and survival.

SLC35B1 is a protein that is known to play a critical role in the regulation of the liver's bile ducts. Bile ducts are specialized tissues that are responsible for the production and circulation of bile, which is a complex mixture of water, fat, and solutes. SLC35B1 is involved in the regulation of the structure and function of bile ducts, which is important for the proper functioning of the liver.

In addition to its role in the regulation of bile ducts, SLC35B1 is also involved in the regulation of the production and release of other proteins that are important for the development and maintenance of tissues and organs. For example, SLC35B1 is involved in the regulation of the production of the protein transmembrane protease (TMPR1), which is a key enzyme that is involved in the production of many different proteins that are involved in the development and maintenance of tissues and organs.

SLC35B1 is also involved in the regulation of the degradation of other proteins that are important for the development and maintenance of tissues and organs. For example, SLC35B1 is involved in the degradation of the protein activator protein (AP-1), which is a key regulator of cell growth and differentiation.

In conclusion, SLC35B1 is a protein that is involved in a wide variety of physiological processes that are important for the development and maintenance of tissues and organs. Its role in the regulation of cellular signaling pathways, the regulation of bile ducts, and the regulation of the production and release of other proteins is well established. Further research is needed to fully understand the unique functions of SLC35B1 and its potential as a drug target or biomarker.

Protein Name: Solute Carrier Family 35 Member B1

Functions: ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane. Imports ATP from the cytosol to the ER lumen and exports ADP in the opposite direction (PubMed:30154480, PubMed:35041824). Regulates ER energy metabolism and protein biogenesis. Appears to be part of a calcium-dependent ER to cytosol low energy response axis, where calcium efflux from ER to the cytosol triggers ATP import into the ER lumen to maintain sufficient ATP supply. Provides ATP to ER chaperone HSPA5 that drives protein folding and trafficking in the ER (PubMed:30154480, PubMed:35041824). Can transport dATP, UTP or UDP in exchange for ATP, but the physiological relevance of this process remains to be established (PubMed:30154480, PubMed:35041824)

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